Michael Töpfer
University of St. Gallen
4 Papers
Michael Töpfer is an academic researcher from University of St. Gallen. The author has contributed to research in topics: Medicine & Hazard ratio. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of Michael Töpfer include Kantonsspital St. Gallen.
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Papers
Axillary dissection versus no axillary dissection in patients with breast cancer and sentinel-node micrometastases (IBCSG 23-01): 10-year follow-up of a randomised, controlled phase 3 trial.
Viviana Galimberti,Bernard F. Cole,Giuseppe Viale,Giuseppe Viale,Paolo Veronesi,Paolo Veronesi,Elisa Vicini,Mattia Intra,Giovanni Mazzarol,Samuele Massarut,Janez Zgajnar,Mario Taffurelli,David Littlejohn,Michael Knauer,Carlo Tondini,Angelo Di Leo,Marco Colleoni,Meredith M. Regan,Alan S. Coates,Richard D. Gelber,Aron Goldhirsch,Frances M. Boyle,Guy Jerusalem,Rolf A. Stahel,Stefan Aebi,Michael D. Green,Per Karlsson,Ingrid Kössler,István Láng,Anita Hiltbrunner,Jürg Bernhard,Stamatina Fournarakou,Roswitha Kammler,Rudolf Maibach,Manuela Rabaglio,Karin Ribi,Heidi Roschitzki,Susanne Roux,Barbara Ruepp,Caitlin Mahoney,Karen N. Price,Lynette Blacher,Tara Scolese,Karolyn Scott,Sandra Lippert,Theresa Zielinski,Mauro G. Mastropasqua,Stefania Andrighetto,Patrizia Dell'Orto,Giuseppe Renne,Giancarlo Pruneri,Silvia Dellapasqua,Monica Iorfida,Giuseppe Cancello,Emilia Montagna,Anna Cardillo,Giulia Peruzzotti,R. Ghisini,Alberto Luini,Umberto Veronesi,Oreste Gentilini,Stefano Zurrida,Giuseppe Curigliano,Franco Nolè,Roberto Orecchia,Marisa Cristina Leonardi,Paola Baratella,Camelia Chifu,Manuela Sargenti,Diana Crivellari,Sandro Morassut,Mario Mileto,Erica Piccoli,Andreas Veronesi,Marisa Donatella Magri,Angelo Buonadonna,Ezio Candiani,Antonino Carbone,Tiziana Perin,Rachele Volpe,Mario Roncadin,Mauro Arcicasa,Francesco Coran,Manuela Lagrassa,Angelo Recalcati,Maria Emanuela Limonta,Paolo Tricomi,Privato Fenaroli,Elisabetta Candiago,Laura Cattaneo,Alberto Gianatti,Donatella Santini,Sylvie Maweja,Philippe Delvenne,Andrée Rorive,Joëlle Collignon,Jean-Remi Garbay,Marie-Christine Mathieu,Hanne Galatius,Jack Hoffmann,Peer Schousen,Charlotte Lanng,John Hoerby,Birgitte Bruun Rasmussen,Helle Holtveg,Maj-Lis Moeller Talman,Julio Abugattas,Jose Manuel Cotrina,Richard Dyer,Jurij Lindtner,Elga Majdic,Snjezana Frkovic-Grazio,Christian Oehlschlegel,Gerhard Ries,Michael Töpfer,Ute Lorenz,Otto Schiltknecht,Bruno Späti,Andreas Ehrsam,Monika Bamert,Martina Egli-Tupaj,Christoph Rageth,Elisabeth Saurenmann,Christoph Tausch,Rosmarie Caduff,Holger Moch,Zsuzsanna Varga,Dimitri Sarlos,Elena Kralidis,Rainer Grobholz,Olivia Pagani,Lucia Bronz,Michele Ghielmini,Luca Mazzucchelli,Tiziana Rusca,Thomas Gyr,Linda Leidi,Giorgio Caccia,Daniel Wyss,Martin F. Fey,Michael Müller,Andreas Günthert,Gilles Berclaz,Achim Fleischmann,Jean Francois Delaloye,Assia Treboux,Hans-Anton Lehr,Maryse Fiche,L Perey,Lucien Zaman,Wendy Jeanneret Sozzi,John F. Forbes,D. F. Lindsay,D.F. Preece,Jane Hill,P. Jeal,P. Smart,John J. Collins,Gregory Bruce Mann,Robert Millar,Craig Murphy,Malcolm Buchanan,Anand Murugasu,James French,Elisabeth Elder,Lynette Mann,David Moon,A. Michael Bilous,Nirmala Pathmanathan,Virginia Howard,Petere G. Gill,James Kollias,Melissa Bochner,Linda Madigan,Elisabeth Rippy,Robert Whitfield,Fereshte Farshidi,Katrina Moore,Mark Sywak,L. Tan,William Ross,Karen Briscoe,Allison Jones,Aashit Shah,Elgene Lim,Robert Macindoe,Andrew J. Spillane,S. Fiona Bonar,Hugh Carmalt,Richard West,Cindy Mak,Paul McKenzie,Richard Harman,Susanne Gerred,Eva Juhasz,Stephen Allpress,Julie Craik,Ian G. Campbell,Paul Chin,Lori Hayes,Frederick Mayall,M. Thorburn +201 more
TL;DR: The findings of the IBCSG 23-01 trial corroborate those obtained at 5 years and are consistent with those of the 10-year follow-up analysis of the Z0011 trial, and support the current practice of not doing an axillary dissection when the tumour burden in the sentinel nodes is minimal or moderate.
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Neoadjuvant chemotherapy and extrapleural pneumonectomy of malignant pleural mesothelioma with or without hemithoracic radiotherapy (SAKK 17/04): a randomised, international, multicentre phase 2 trial
Rolf A. Stahel,Oliver Riesterer,A. Xyrafas,Isabelle Opitz,Michael Beyeler,Adrian F. Ochsenbein,Martin Früh,Richard Cathomas,Kristiaan Nackaerts,Solange Peters,Christoph Mamot,Alfred Zippelius,Carlo Mordasini,Clemens B. Caspar,K. Eckhardt,Ralph A. Schmid,Daniel M. Aebersold,O. Gautschi,Wolfgang Nagel,Michael Töpfer,Jerome Krayenbuehl,Karin Ribi,llja F Ciernik,Walter Weder +23 more
TL;DR: The findings do not support the routine use of hemithoracic radiotherapy for malignant pleural mesothelioma after neoadjuvant chemotherapy and extrapleural pneumonectomy.
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Concomitant cisplatin and hyperfractionated radiotherapy in locally advanced head and neck cancer: 10-year follow-up of a randomized phase III trial (SAKK 10/94).
Pirus Ghadjar,Mathew Simcock,Gabriela Studer,Abdelkarim S. Allal,Mahmut Ozsahin,Jacques Bernier,Michael Töpfer,Frank Zimmermann,Michael Betz,Christoph Glanzmann,Daniel M. Aebersold +10 more
TL;DR: After long-term follow-up, combined-treatment with cisplatin and hyperfractionated radiotherapy maintained improved rates of locoregional control, distant metastasis-free survival, and cancer-specific survival compared to that of hyperfracted radiotherapy alone, with no difference in major late toxicity.
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Concomitant Cisplatin Significantly Improves Locoregional Control in Advanced Head and Neck Cancers Treated With Hyperfractionated Radiotherapy
Pia Huguenin,Karl T. Beer,Abdelkarim S. Allal,Kaspar Rufibach,Corinne Friedli,Jacques Bernard Davis,Bernhard C. Pestalozzi,Stephan Schmid,Armin Thöni,Mahmut Ozsahin,Jacques Bernier,Michael Töpfer,Roger Kann,Urs R. Meier,Peter Thum,Sabine Bieri,Markus Notter,Norbert Lombriser,Christoph Glanzmann +18 more
TL;DR: The therapeutic index of hyperfractionated radiotherapy is improved by concomitant cisplatin, and locally advanced and/or node-positive nonmetastatic carcinomas of the head and neck with squamous cell carcinomas are treated.