Michael Tanowitz
University of California, San Francisco
10 Papers
175 Citations
Michael Tanowitz is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: G protein-coupled receptor & Receptor. The author has an hindex of 5, co-authored 7 publications. Previous affiliations of Michael Tanowitz include University of California.
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Papers
A Novel Endocytic Recycling Signal Distinguishes Biological Responses of Trk Neurotrophin Receptors
TL;DR: The results indicate that TrkA receptors, which predominantly recycle in signal-dependent manner, have unique biological properties dictated by its specific endocytic trafficking itinerary.
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Association of Mu-Opioid Receptor Variants and Response to Citalopram Treatment in Major Depressive Disorder
Holly A. Garriock,Michael Tanowitz,Jeffrey B. Kraft,Vu C. Dang,Eric Peters,Greg D. Jenkins,Megan S. Reinalda,Patrick J. McGrath,Mark von Zastrow,Susan L. Slager,Steven P. Hamilton +10 more
TL;DR: These results suggest that rates of response to antidepressants and consequent remission from major depressive disorder are influenced by variation in the mu-opioid receptor gene as a result of either an effect on placebo response or true pharmacologic response.
Alternative splicing determines the post-endocytic sorting fate of G-protein-coupled receptors.
TL;DR: The present results are the first to establish a role of alternative RNA processing in specifying the post-endocytic sorting of G-protein-coupled receptors between divergent and functionally distinct membrane pathways.
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Identification of protein interactions by yeast two-hybrid screening and coimmunoprecipitation.
TL;DR: The yeast two-hybrid screen and coimmunoprecipitation are a useful way to identify and sort through candidate GPCR-interacting proteins prior to analysis in physiological studies.
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Agonist-Induced Desensitization and Endocytosis of G-protein-Coupled Receptors
Michael Tanowitz,Mark von Zastrow +1 more
- 01 Jan 2010
TL;DR: This chapter explains the agonist-induced desensitization and endocytosis of G-protein-coupled receptors and focuses primarily on well-characterized mechanisms that appear to be relevant to the regulation of many GPCRs.
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