Michael Schofield
University of Sussex
7 Papers
32 Citations
Michael Schofield is an academic researcher from University of Sussex. The author has contributed to research in topics: Lymnaea & Biology. The author has an hindex of 6, co-authored 7 publications.
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Papers
Activation of MAPK is necessary for long-term memory consolidation following food-reward conditioning.
Maria J. Ribeiro,Michael Schofield,Ildikó Kemenes,Michael O'Shea,György Kemenes,Paul R. Benjamin +5 more
TL;DR: Although an increase in MAPK phosphorylation was shown to be essential for food-reward conditioning, it was also detected in snails that were exposed to the conditioned stimulus or the unconditioned stimulus, suggesting that phosphorylated of MAPK is necessary but not sufficient for learning to occur.
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Neuronal expression of an FMRFamide-gated Na+ channel and its modulation by acid pH.
TL;DR: The presence of an FMRFamide-gated sodium current with features expected for a FaNaC: amiloride sensitivity, sodium selectivity, specificity for F MRFamide and Phe-Leu-Arg-Phe-amide (FLRFamide), and no dependency on G-protein coupling is demonstrated.
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Small cardioactive peptide gene: structure, expression and mass spectrometric analysis reveals a complex pattern of co-transmitters in a snail feeding neuron.
TL;DR: Identical stimulatory activity for the two SCP peptides was demonstrated by their application to the isolated foregut, suggesting that their co‐release from the B2 cells may play an important part in the co‐modulation of gut motility, together with acetylcholine and the myomodulin family of peptides.
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Characterization of NO-sensitive guanylyl cyclase: expression in an identified interneuron involved in NO-cGMP-dependent memory formation
Maria J. Ribeiro,Volko A. Straub,Michael Schofield,Jo Picot,Paul R. Benjamin,Michael O'Shea,Sergei Korneev +6 more
TL;DR: Cl cloning and characterization of both α and β subunits of NO‐sensitive sGC are reported and shown to be coexpressed in the CGCs and it is demonstrated that this depolarization is blocked by ODQ, supporting the hypothesis that it is mediated by sGC.
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Acetylcholine binding protein of mollusks is unlikely to act as a regulator of cholinergic neurotransmission at neurite-neurite synaptic sites in vivo
TL;DR: It is demonstrated here that AChBP expression is confined to a subpopulation of glial cells located within the peripheral zone of each of the ganglia constituting the CNS, and suggested that A ChBP functions in vivo as a regulator of nonsynaptic cholinergic transmission.
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