Michael S. Huh
Ottawa Hospital Research Institute
20 Papers
60 Citations
Michael S. Huh is an academic researcher from Ottawa Hospital Research Institute. The author has contributed to research in topics: Biology & Oncolytic virus. The author has an hindex of 12, co-authored 18 publications. Previous affiliations of Michael S. Huh include University of Ottawa.
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Papers
Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis.
Shihuan Kuang,Sophie Chargé,Patrick Seale,Michael S. Huh,Michael A. Rudnicki,Michael A. Rudnicki +5 more
TL;DR: It is concluded that interstitial Pax3+ cells represent a novel myogenic population that is distinct from the sublaminar satellite cell lineage and that Pax7 is essential for the formation of functional myogenic progenitors from sublaminated satellite cells.
Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1α
Anthony Scimè,Guillaume Grenier,Michael S. Huh,Mark A. Gillespie,Lisa Bevilacqua,Mary-Ellen Harper,Michael A. Rudnicki +6 more
TL;DR: In this paper, the Rb family, Rb, p107, p130, and pRb play important roles in cell cycle control and cellular differentiation, and Rb has been suggested to regulate adipocyte differentiation.
233
VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection
Rozanne Arulanandam,Cory Batenchuk,Fernando A. Angarita,Kathryn Ottolino-Perry,Sophie Cousineau,Amelia Mottashed,Emma Burgess,Theresa Falls,Naomi De Silva,Jovian Tsang,Grant A. Howe,Marie-Claude Bourgeois-Daigneault,David P. Conrad,Manijeh Daneshmand,Caroline J. Breitbach,David H. Kirn,Leda Raptis,Subash Sad,Harold L. Atkins,Michael S. Huh,Jean-Simon Diallo,Brian D. Lichty,Carolina S. Ilkow,Fabrice Le Boeuf,Christina L. Addison,J. Andrea McCart,J. Andrea McCart,John C. Bell +27 more
TL;DR: In vivo suppression of VEGF signaling diminishes PRD1-BF1/Blimp1 expression in tumor vasculature and inhibits intravenously administered oncolytic vaccinia delivery to and consequent spread within the tumor.
96
Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation
Matías Alvarez-Saavedra,Matías Alvarez-Saavedra,Yves De Repentigny,Pamela S. Lagali,Edupuganti V.S. Raghu Ram,Keqin Yan,Emile Hashem,Emile Hashem,Danton Ivanochko,Danton Ivanochko,Michael S. Huh,Doo Yang,Alan J. Mears,Matthew A. M. Todd,Matthew A. M. Todd,Chelsea P. Corcoran,Erin A. Bassett,Nicholas Tokarew,Juraj Kokavec,Romit Majumder,Ilya Ioshikhes,Valerie A. Wallace,Valerie A. Wallace,Rashmi Kothary,Rashmi Kothary,Eran Meshorer,Tomas Stopka,Arthur I. Skoultchi,David J. Picketts,David J. Picketts +29 more
TL;DR: It is shown that mice conditionally inactivated for Snf2h in neural progenitors have reduced levels of histone H1 and H2A variants that compromise chromatin fluidity and transcriptional programs within the developing cerebellum.
84
ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity.
Courtney A. Lovejoy,Kaori K. Takai,Michael S. Huh,David J. Picketts,David J. Picketts,Titia de Lange +5 more
TL;DR: The data reveal that ATRX has an effect on telomeric DSB repair and that this role involves both telomere cohesion and a DAXX-dependent pathway.