Michael R. Blackburn
University of Texas Health Science Center at Houston
211 Papers
2.8K Citations
Michael R. Blackburn is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Adenosine & Adenosine deaminase. The author has an hindex of 63, co-authored 205 publications. Previous affiliations of Michael R. Blackburn include University of Texas at Austin & Thomas Jefferson University.
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Papers
P2Y6 and vascular inflammation
TL;DR: In this issue of Blood, Riegel and colleagues demonstrate that inflammatory stimuli induce the expression of the P2Y6 receptor on the vascular endothelium where it serves to enhance systemic inflammatory responses.
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Soy Formula Is Not Estrogenic and Does Not Result in Reproductive Toxicity in Male Piglets: Results from a Controlled Feeding Study
Martin J. J. Ronis,Horacio Gomez-Acevedo,Kartik Shankar,Leah Hennings,N. Sharma,Michael R. Blackburn,Isabelle R. Miousse,Harry D. Dawson,Celine Chen,Kelly E. Mercer,Thomas M. Badger +10 more
TL;DR: In this article , male White-Dutch Landrace piglets received either sow milk (Sow), or were provided milk formula (Milk), soy formula (Soy), milk formula supplemented with 17-beta-estradiol (2 mg/kg/d), or supplemented with genistein (84 mg/L of diet; (M + G) from postnatal day 2 until day 21.
Adenosine Is A Common Factor Regulating Erythrocyte 2,3-Bisphosphate Induction In Normal Individuals At High Altitude and In Patients With Sickle Cell Disease
Yujin Zhang,Hong Liu,Kaiqi Sun,Anren Song,Harry Karmouty-Quintana,Ning Yuan Chen,Almut Grenz,Rodney E. Kellems,Modupe Idowu,Harinder S. Juneja,Robert C. Roach,Holger K. Eltzschig,Michael R. Blackburn,Yang Xia +13 more
TL;DR: In vivo physiological relevance and pharmacologic and genetic evidence are provided that elevated adenosine signaling via ADORA2B contributes to elevated of 2,3-BPG production and thereby triggers O2 release from erythrocytes.
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Purine metabolic disturbances in adenosine deaminase deficient fetuses and placentae: A protective role for this enzyme during murine development
TL;DR: The trophoblast cells which normally contain greater than 95% of the ADA found in the fetal conceptus, are not damaged in the absence of ADA, indicating placental ADA plays an important role in protecting the developing embryo and fetus from potentially cytotoxic nucleosides.
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