Michael R. Blackburn
University of Texas Health Science Center at Houston
211 Papers
2.8K Citations
Michael R. Blackburn is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Adenosine & Adenosine deaminase. The author has an hindex of 63, co-authored 205 publications. Previous affiliations of Michael R. Blackburn include University of Texas at Austin & Thomas Jefferson University.
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Papers
Effect of antigen sensitization and challenge on oscillatory mechanics of the lung and pulmonary inflammation in obese carboxypeptidase E-deficient mice
Paul H. Dahm,Jeremy B. Richards,Harry Karmouty-Quintana,Kevin R. Cromar,Sanjiv Sur,Roger E. Price,Farhan Malik,Chantal Y. Spencer,Ramon X. Barreno,S. Shahrukh Hashmi,Michael R. Blackburn,Ikram U. Haque,Richard A. Johnston +12 more
TL;DR: It is demonstrated that OVA sensitization and challenge enhance airway obstruction in obese mice regardless of the genetic basis of obesity, whereas the degree of OVA-induced pulmonary inflammation is dependent on the genetic modality of obesity induction.
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Effect of antigen sensitization and challenge on oscillatory
Paul H. Dahm,Jeremy B. Richards,Harry Karmouty-Quintana,Kevin R. Cromar,Farhan Malik,Chantal Y. Spencer,Ramon X. Barreno,S Syed,Michael R. Blackburn,Ikram U. Haque,Richard A. Johnston +10 more
- 01 Jan 2014
TL;DR: In this paper, the authors examined indices of these sequelae in mice obese due to a genetic deficiency in carboxypeptidase E, an enzyme that processes pro-hormones and pro-neuropeptides involved in satiety and energy expenditure.
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•Journal Article
Certain Surfactants Show Promise in the Therapy of Pulmonary Tuberculosis
James K. Stoops,Ranjana Arora,Lisa Armitage,Audrey Wanger,Ling Song,Michael R. Blackburn,Gerhard R. F. Krueger,Semyon A. Risin +7 more
TL;DR: It is established that certain surfactants are proficient in removing MTB's shield and, because they are well known as cell permeabilizing agents, they may also enhance the effectiveness of antibiotics and the immune system's response in the treatment of pulmonary TB.
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Nox4 expression in osteo-progenitors controls bone development in mice during early life
Jin-Ran Chen,Oxana P. Lazarenko,Michael R. Blackburn,Jennifer F. Chen,Christopher E. Randolph,Jovanny Zabaleta,K. Schroder,Kim Brint Pedersen,Martin J. J. Ronis +8 more
TL;DR: In this paper , the role of Nox4 in osteo-progenitors during postnatal bone development was investigated in both sexes, and the results showed that under-developed bone formation in 3-week old CKO and Nox-4-/- mice quickly caught up to levels of control mice by 6-week of age, remained no different at 13-week-of age, and was reversed in 32-week older male mice compared with control mice.
Transitory expression of the a2b adenosine receptor during implantation chamber development
Michael R. Blackburn,Michael R. Blackburn,J.A. Wubah,J.A. Wubah,Janci L. Chunn,Linda F. Thompson,Thomas B. Knudsen +6 more
TL;DR: Uterine adenosine surges to levels sufficient for A2b receptor engagement during a defined period (i.e., days 4–6) after blastocyst implantation, which defines a transitory window of murine gestation that corresponds to a period of human gestation encompassing most spontaneous pregnancy losses.
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