Michael R. Benoit
Stanford University
18 Papers
32 Citations
Michael R. Benoit is an academic researcher from Stanford University. The author has contributed to research in topics: Biology & Carbonic anhydrase. The author has an hindex of 14, co-authored 18 publications. Previous affiliations of Michael R. Benoit include Codexis & University of Colorado Boulder.
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Papers
Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas
Oscar Alvizo,Luan J. Nguyen,Christopher Savile,Jamie A. Bresson,Satish Lakhapatri,Earl O. P. Solis,Richard J. Fox,James Michael Broering,Michael R. Benoit,Sabrina A. Zimmerman,Scott J. Novick,Jack Liang,James Lalonde +12 more
TL;DR: A β-class carbonic anhydrase was engineered using directed evolution to withstand some of the harshest conditions associated with an industrial carbon capture process, resulting in a 4,000,000-fold improvement over the natural enzyme.
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Escherichia coli biofilms formed under low-shear modeled microgravity in a ground-based system
TL;DR: Bacterial biofilms of a mutant of E. coli, deficient in sigma(s), were impaired in developing LSMMG-conferred resistance to the general stressors but not to the antibiotics, indicating two separate pathways of LS MMG- Conferred resistance.
Microgravity, bacteria, and the influence of motility
Michael R. Benoit,David M. Klaus +1 more
TL;DR: A trend relating cell motility to experimental outcome is identified and related studies conducted in microgravity analog devices, such as the clinostat or rotating wall vessel bioreactor, further corroborate this trend.
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Role of the rapA Gene in Controlling Antibiotic Resistance of Escherichia coli Biofilms
Susan V. Lynch,L. Dixon,Michael R. Benoit,Eoin L. Brodie,M. Keyhan,Ping Hu,David F. Ackerley,Gary L. Andersen,Abdul Matin +8 more
TL;DR: The results strongly suggest a dual mechanism for the wild-type biofilm penicillin G resistance, retarded penetration, and effective efflux.
Microbial antibiotic production aboard the International Space Station
Michael R. Benoit,W. Li,Louis S. Stodieck,Kin Sing Lam,Kin Sing Lam,C. L. Winther,Timberley M. Roane,David M. Klaus +7 more
TL;DR: Microbial antibiotic production was examined onboard the International Space Station during the 72-day 8A increment and findings of increased productivity of actinomycin D by Streptomyces plicatus in space corroborated with previous findings for the early sample points; however, the flight production levels were lower than the matched ground control samples for the remainder of the mission.
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