Michael P. Frenneaux
University of East Anglia
374 Papers
2.6K Citations
Michael P. Frenneaux is an academic researcher from University of East Anglia. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 68, co-authored 364 publications. Previous affiliations of Michael P. Frenneaux include University of Queensland & Hammersmith Hospital.
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Papers
Effects of insulin lispro and chronic vitamin C therapy on postprandial lipaemia, oxidative stress and endothelial function in patients with type 2 diabetes mellitus
Marc Evans,Richard Anderson,J.C. Smith,Niaz Khan,J.M. Graham,Andrew Thomas,Keith Morris,D. Deely,Michael P. Frenneaux,JS Davies,Aled Rees +10 more
TL;DR: This study assessed endothelial function and OS during PPL following insulin and vitamin C, which is a feature of diabetic dyslipidaemia affecting CVD via enhanced oxidative stress (OS) and endothelial dysfunction.
Cardiovascular Magnetic Resonance Determinants of Left Ventricular Noncompaction
Dana Dawson,David J. McLernon,Vimal Raj,Alicia M. Maceira,Sanjay K Prasad,Michael P. Frenneaux,Dudley J. Pennell,Philip J. Kilner +7 more
TL;DR: A new, refined, diagnostic tool for identifying left ventricular noncompaction (LVNC) is developed, based on an a priori assessment of the trabecular architecture in healthy volunteers.
The effect of GH replacement therapy on endothelial function and oxidative stress in adult growth hormone deficiency
L. M. Evans,JS Davies,Richard Anderson,Gethin Ellis,Simon K. Jackson,Malcolm J. Lewis,Michael P. Frenneaux,Aled Rees,Maurice F. Scanlon +8 more
TL;DR: This study suggests plausible mechanisms underlying any proatherogenic tendency in adult GHD and demonstrates improvement of these factors following GH replacement.
Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite
Abdul R. Maher,Sayqa Arif,Melanie Madhani,Khalid Abozguia,Ibrar Ahmed,Bernadette O. Fernandez,Martin Feelisch,Aine G. O'Sullivan,Arthur Christopoulos,Aaron L. Sverdlov,D. Ngo,Rustem Dautov,Philip E. James,John D. Horowitz,Michael P. Frenneaux +14 more
TL;DR: The aim of the current study was to compare the haemodynamic effects of NO2− in healthy volunteers and patients with stable congestive heart failure (CHF).
The pathophysiology of heart failure with preserved ejection fraction: from molecular mechanisms to exercise haemodynamics.
TL;DR: In this article, the molecular aspects of HfpEF as well as the profoundly disturbed haemodynamics with particular focus on exercise haemodynamic abnormalities are discussed and a review is presented.