Michael J. Yetman
Baylor College of Medicine
11 Papers
3 Citations
Michael J. Yetman is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Biology & Rett syndrome. The author has an hindex of 8, co-authored 11 publications. Previous affiliations of Michael J. Yetman include Max Planck Society.
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Papers
Wild-type microglia do not reverse pathology in mouse models of Rett syndrome
Jieqi Wang,Jan Eike Wegener,Teng-Wei Huang,Smitha Sripathy,Héctor De Jesús-Cortés,Héctor De Jesús-Cortés,Pin Xu,Stephanie Tran,Whitney Knobbe,Vid Leko,Jeremiah K. Britt,Ruth Starwalt,Latisha McDaniel,Christopher S. Ward,Diana C. Parra,Benjamin Newcomb,Uyen Lao,Cynthia Nourigat,David A. Flowers,Sean M Cullen,Nikolas L. Jorstad,Yue Yang,Lena Glaskova,Sébastien Vigneau,Julia Kozlitina,Michael J. Yetman,Joanna L. Jankowsky,Sybille D. Reichardt,Holger M. Reichardt,Jutta Gärtner,Marisa S. Bartolomei,Min Fang,Min Fang,Keith R. Loeb,Keith R. Loeb,C. Dirk Keene,Irwin D. Bernstein,Margaret A. Goodell,Daniel J. Brat,Peter Huppke,Jeffrey L. Neul,Antonio Bedalov,Antonio Bedalov,Andrew A. Pieper,Andrew A. Pieper +44 more
TL;DR: It is found that despite robust microglial engraftment, BMT from wild-type donors did not prevent early death or ameliorate neurological deficits, and early and specific MECp2 genetic expression in microglia did not rescue Mecp2-deficient mice.
185
Specificity and efficiency of reporter expression in adult neural progenitors vary substantially among nestin-CreER(T2) lines.
TL;DR: The findings suggest that each nestin‐CreERT2 line may best serve different experimental needs, depending on whether specificity or efficiency is of greatest concern, and demonstrates that each new pair of driver and responder lines should be evaluated independently, as both components can significantly influence the resulting expression pattern.
84
Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability
Rong Zhao,Stacy D. Grunke,M. M. Keralapurath,Michael J. Yetman,Alexander Lam,Tang-Cheng Lee,Konstantinos Sousounis,Yongying Jiang,Deborah A. Swing,Lino Tessarollo,Daoyun Ji,Joanna L. Jankowsky +11 more
TL;DR: A chemogenetic model for non-invasive neuronal silencing that offers multiple advantages over existing strategies in this setting is introduced and shows that manipulation of entorhinal activity destabilizes spatial coding and disrupts spatial memory.
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Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction.
TL;DR: It is found that Aβ and tau had independent effects on locomotion, learning, and memory, but found no behavioral evidence for an interaction between the two transgenes, suggesting that robust amyloid pathology within the medial temporal lobe has little effect on the metabolism of wild type human tau in this model.
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Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
Jieqi Wang,Jan Eike Wegener,Teng-Wei Huang,Smitha Sripathy,Héctor De Jesús-Cortés,Pin Xu,Stephanie Tran,Whitney Knobbe,Vid Leko,Jeremiah K. Britt,Ruth Starwalt,Latisha McDaniel,Christopher S. Ward,Diana C. Parra,Benjamin Newcomb,Uyen Lao,Cynthia Nourigat,David A. Flowers,Sean M Cullen,Nikolas L. Jorstad,Yue Yang,Lena Glaskova,Sébastien Vigneau,Julia Kozlitina,Michael J. Yetman,Joanna L. Jankowsky,Sybille D. Reichardt,Holger M. Reichardt,Jutta Gärtner,Marisa S. Bartolomei,Min Fang,Keith R. Loeb,C. Dirk Keene,Irwin D. Bernstein,Margaret A. Goodell,Daniel J. Brat,Peter Huppke,Jeffrey L. Neul,Antonio Bedalov,Andrew A. Pieper +39 more
TL;DR: In this paper, the first name of author Sebastien Vingeau was misspelled as Sebastien and the labels (WT→KO) of the two bottom panels in Extended Data Figure 1b were swapped.