Michael J. Yaszemski
Mayo Clinic
388 Papers
3K Citations
Michael J. Yaszemski is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Medicine & Bone regeneration. The author has an hindex of 77, co-authored 379 publications. Previous affiliations of Michael J. Yaszemski include Paracelsus Private Medical University of Salzburg & University of Rochester.
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Papers
Decreased local and systemic levels of sFRP3 protein in osteosarcoma patients.
Dalibel Bravo,Ahmet Salduz,Kristen L. Shogren,Madison N. Okuno,James L. Herrick,Scott H. Okuno,Mario Galindo,Andre J. van Wijnen,Michael J. Yaszemski,Avudaiappan Maran +9 more
TL;DR: The findings show that the systemic and local levels of sFRP3 protein are downregulated in osteosarcoma and s FRP3 levels could be explored further in the diagnosis and the care of osteosARcoma patients.
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Hydrogel-PLGA delivery system prolongs 2-methoxyestradiol-mediated anti-tumor effects in osteosarcoma cells
Avudaiappan Maran,Mahrokh Dadsetan,Colleen M. Buenz,Kristen L. Shogren,Lichun Lu,Michael J. Yaszemski +5 more
TL;DR: The findings show that the OPF and PLGA polymeric system may prove to be useful in controlled and sustained delivery of 2-ME and could be further explored in the treatment of osteosarcoma.
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Solute Transport in Cyclically Deformed Porous Tissue Scaffolds with Controlled Pore Cross-Sectional Geometries
Jorn Op Den Buijs,Lichun Lu,Steven M. Jorgensen,Dan Dragomir-Daescu,Michael J. Yaszemski,Erik L. Ritman +5 more
TL;DR: Results show that application of cyclic strain significantly increases the rate and depth of solute transport, as compared to diffusive transport alone, for all pore shapes, and pore shape, pore size, and the orientation of the pore cross-sectional asymmetry with respect to the direction of strain greatly influence Solute transport.
Preclinical Bone Repair Models in Regenerative Medicine
Elvis L. Francois,Michael J. Yaszemski +1 more
- 01 Jan 2019
TL;DR: This chapter provides an overview of current trends in bone tissue engineering (BTE) in regenerative medicine and focuses on the building blocks of bone regeneration in BTE: cells, growth/differentiation factors and scaffolds.
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Patent
Block Copolymers of Polycarpolactone and Poly (Propylene Funarate)
Shanfeng Wang,Michael J. Yaszemski,Lichun Lu,Bradford L. Currier +3 more
- 18 Nov 2005
TL;DR: In this paper, a block copolymer of poly(propylene fumarate) and poly(caprolactone) diol is used to produce a self-crosslinkable and photocrosslinkable scaffold for tissue and/or skeletal reconstruction.
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