Michael J. Yaszemski
Mayo Clinic
388 Papers
3K Citations
Michael J. Yaszemski is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Medicine & Bone regeneration. The author has an hindex of 77, co-authored 379 publications. Previous affiliations of Michael J. Yaszemski include Paracelsus Private Medical University of Salzburg & University of Rochester.
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Papers
Germline TGF‐β receptor mutations and skeletal fragility: A report on two patients with Loeys–Dietz syndrome
Salman Kirmani,Peter J. Tebben,Aida N. Lteif,David Gordon,Bart L. Clarke,Theresa E. Hefferan,Michael J. Yaszemski,Pamela S. McGrann,Noralane M. Lindor,Jay W. Ellison +9 more
TL;DR: Osteopenia or osteoporosis may become increasingly important issues as earlier detection and treatment of the vascular complications of LDS improves life expectancy in these patients.
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Comparison of Cellular Architecture, Axonal Growth, and Blood Vessel Formation Through Cell-Loaded Polymer Scaffolds in the Transected Rat Spinal Cord
Nicolas N. Madigan,Bingkun K. Chen,Andrew M. Knight,Gemma E. Rooney,Eva Sweeney,Lisa Kinnavane,Michael J. Yaszemski,Peter Dockery,Timothy O'Brien,Siobhan S. McMahon,Anthony J. Windebank +10 more
TL;DR: In conclusion, Schwann cells and eGFP-MSCs influenced the regenerating microenvironment with lasting effect on axonal and blood vessel growth and provided insight into physiologic characteristics that may support axon regeneration.
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In vitro and In vivo Release of Nerve Growth Factor from Biodegradable Poly-Lactic-Co-Glycolic-Acid Microspheres
Ralph de Boer,Andrew M. Knight,Robert J. Spinner,Martijn J. A. Malessy,Michael J. Yaszemski,Anthony J. Windebank +5 more
TL;DR: On the basis of the surface morphology and release profiles, microspheres fabricated from 50:50 4A PLGA to be best suited for the use in a rat sciatic nerve injury model are found.
Enhanced Bone Morphogenetic Protein-2-Induced Ectopic and Orthotopic Bone Formation by Intermittent Parathyroid Hormone (1–34) Administration
Diederik H.R. Kempen,Lichun Lu,Theresa E. Hefferan,Laura B. Creemers,Andras Heijink,Avudaiappan Maran,Wouter J.A. Dhert,Michael J. Yaszemski +7 more
TL;DR: It is suggested that intermittent administration of a low PTH dose alone has limited potential to enhance local bone regeneration in a critical-sized defect in rats, however, when combined with local BMP-2-releasing scaffolds, PTH administration significantly enhanced osteogenesis in both ectopic and orthotopic sites.
Potential of hydrogels based on poly(ethylene glycol) and sebacic acid as orthopedic tissue engineering scaffolds.
TL;DR: PEGSDA hydrogel scaffolds without further modification may be useful as orthopedic tissue engineering scaffolds as well as local drug carriers for prolonged sustained release of osteoinductive molecules.
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