Michael J. Yaszemski
Mayo Clinic
388 Papers
3K Citations
Michael J. Yaszemski is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Medicine & Bone regeneration. The author has an hindex of 77, co-authored 379 publications. Previous affiliations of Michael J. Yaszemski include Paracelsus Private Medical University of Salzburg & University of Rochester.
Chat about Author
Papers
Controlled release of vascular endothelial growth factor using poly-lactic-co-glycolic acid microspheres: In vitro characterization and application in polycaprolactone fumarate nerve conduits
Jing Rui,Mahrokh Dadsetan,M. Brett Runge,Robert J. Spinner,Michael J. Yaszemski,Anthony J. Windebank,Huan Wang,Huan Wang +7 more
TL;DR: This study established a novel system for controlled release of growth factors and enables in vivo studies of nerve conduits conditioned with this system and confirms that VEGF retained its bioactivity throughout the 4 week time period.
81
Fungal infections of the spine
TL;DR: Resistance to medical therapy, spinal instability, and neurologic deficits are indications for débridement and stabilization with spinal fusion, and prognosis depends on the premorbid state of the patient, the type of fungal organism, and the timing of treatment.
76
Mechanical effects of partial sacrectomy: when is reconstruction necessary?
TL;DR: Group I pelves could withstand postoperative mobilization without fracture, whereas Group II would probably not, and Reconstruction should therefore be considered when performing transverse partial sacrectomy above the S1 nerve root.
75
Controlled release of doxorubicin from pH-responsive microgels
TL;DR: P pH-responsive microgels for the delivery of doxorubicin (DOX) are developed in order to optimize its anti-tumor activity while minimizing its systemic toxicity.
74
Histone deacetylase 3 is required for maintenance of bone mass during aging
Meghan E. McGee-Lawrence,Elizabeth W. Bradley,Amel Dudakovic,Samuel W. Carlson,Zachary C. Ryan,Rajiv Kumar,Mahrokh Dadsetan,Michael J. Yaszemski,Qingshan Chen,Kai Nan An,Jennifer J. Westendorf +10 more
TL;DR: Osteoblasts and osteocytes from Hdac3 CKO(OCN) mice showed increased DNA damage and reduced functional activity in vivo and in vitro, suggesting that HdAC3 expression in osteoblastsand osteocytes is essential for bone maintenance during aging.
72