Michael Gebert
University of Freiburg
14 Papers
67 Citations
Michael Gebert is an academic researcher from University of Freiburg. The author has contributed to research in topics: Translocase of the inner membrane & Translocase. The author has an hindex of 12, co-authored 12 publications. Previous affiliations of Michael Gebert include Harvard University.
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Papers
Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale
Marcel Morgenstern,Sebastian B. Stiller,Philipp Lübbert,Christian D. Peikert,Stefan Dannenmaier,Friedel Drepper,Uri Weill,Philipp Höß,Reinhild Feuerstein,Michael Gebert,Maria Bohnert,Martin van der Laan,Maya Schuldiner,Conny Schütze,Silke Oeljeklaus,Nikolaus Pfanner,Nils Wiedemann,Bettina Warscheid +17 more
TL;DR: The integrative proteome provides a high-confidence source for the characterization of physiological and pathophysiological functions of mitochondria and their integration into the cellular environment.
425
Macromolecular Assemblies of the Mammalian Circadian Clock.
Rajindra P. Aryal,Pieter Bas Kwak,Alfred Tamayo,Michael Gebert,Po-Lin Chiu,Thomas Walz,Charles J. Weitz +6 more
TL;DR: The mammalian circadian clock is built on a feedback loop in which PER and CRY proteins repress their own transcription, and in mouse liver nuclei all three PERs are present together in an ∼1.9-MDa repressor assembly that quantitatively incorporates its CLOCK-BMAL1 transcription factor target.
243
Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane.
Natalia Gebert,Michael Gebert,Silke Oeljeklaus,Karina von der Malsburg,David A. Stroud,Bogusz Kulawiak,Christophe Wirth,René P. Zahedi,Pavel Dolezal,Sebastian Wiese,Oliver Simon,Agnes Schulze-Specking,Kaye N. Truscott,Kaye N. Truscott,Albert Sickmann,Peter Rehling,Bernard Guiard,Carola Hunte,Bettina Warscheid,Martin van der Laan,Nikolaus Pfanner,Nils Wiedemann +21 more
TL;DR: It is concluded that the assembly of Sdh3 with different partner proteins, Sdh4 and Tim18, recruits it to two different mitochondrial membrane complexes with functions in bioenergetics and protein biogenesis, respectively.
145
Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane.
Raffaele Ieva,Sandra G. Schrempp,Łukasz Opaliński,Florian Wollweber,Philipp Höß,Anna K. Heißwolf,Michael Gebert,Ying Zhang,Bernard Guiard,Sabine Rospert,Thomas Becker,Agnieszka Chacinska,Nikolaus Pfanner,Martin van der Laan +13 more
TL;DR: It is concluded that Mgr2 functions as a lateral gatekeeper of the mitochondrial presequence translocase, providing quality control for the membrane sorting of preproteins.
102
Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes
Michael Gebert,Sandra G. Schrempp,Carola S. Mehnert,Anna K. Heißwolf,Silke Oeljeklaus,Raffaele Ieva,Maria Bohnert,Karina von der Malsburg,Sebastian Wiese,Thomas Kleinschroth,Carola Hunte,Helmut E. Meyer,Ilka Haferkamp,Bernard Guiard,Bettina Warscheid,Nikolaus Pfanner,Martin van der Laan +16 more
TL;DR: Mgr2 is a new component of the mitochondrial presequence translocase required for efficient coupling of the TIM23 core complex to Tim21, respiratory chain complexes, and the translocases of the outer mitochondrial membrane.
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