Michael E Abram
AstraZeneca
8 Papers
15 Citations
Michael E Abram is an academic researcher from AstraZeneca. The author has contributed to research in topics: Medicine & Molecular epidemiology. The author has an hindex of 2, co-authored 8 publications.
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Papers
Disease Burden Estimates of Respiratory Syncytial Virus related Acute Respiratory Infections in Adults With Comorbidity: A Systematic Review and Meta-Analysis.
Ting Shi,Sophie Vennard,Francis Jasiewicz,Rory Brogden,Harish Nair,Harry Campbell,You Li,Peter J. M. Openshaw,Philippe Beutels,Louis Bont,Andrew J. Pollard,Eva Molero,Federico Martinón-Torres,Terho Heikkinen,Adam Meijer,Thea Kølsen Fischer,Maarten van den Berge,Carlo Giaquinto,Michael E Abram,Kena A. Swanson,Sonia K Stoszek,Jean-Yves Pirçon,Scott Gallichan,Clarisse Demont,Jeroen Aerssens,Arnaud Cheret,Gabriela Ispas,Paul Peeters,Brian Rosen,Robert Fuentes,Ann R. Falsey,Rafael T. Mikolajczyk,Larry J. Anderson,Resceu Investigators +33 more
TL;DR: The authors in this article estimated the incidence, hospitalization rate, and in-hospital case fatality ratio (hCFR) of RSV-ARI in adults with comorbidities based on a systematic review of studies published between January 1996 and March 2020.
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Global molecular diversity of RSV – the “INFORM RSV” study
Annefleur C Langedijk,Robert Jan Lebbink,Christiana A. Naaktgeboren,Anouk Evers,Marco C. Viveen,Anne Greenough,Terho Heikkinen,Renato T. Stein,Peter Richmond,Federico Martinón-Torres,Marta C. Nunes,Mitsuaki Hosoya,Christian Keller,Monika Bauck,Robert Cohen,Jesse Papenburg,Jeffrey M. Pernica,Marije P. Hennus,Hong Jin,David E. Tabor,Andrev Tovchigrechko,Alexey Ruzin,Michael E Abram,Deidre E. Wilkins,Joanne G. Wildenbeest,Leyla Kragten-Tabatabaie,Frank E. J. Coenjaerts,Mark T. Esser,Louis Bont +28 more
TL;DR: INFORM is a prospective, multicenter, global clinical study performed by ReSViNET to investigate the worldwide molecular diversity of RSV isolates collected from children less than 5 years of age and will provide insight into the molecular epidemiology of circulating RSV strains worldwide.
Hospital Admission Trends for Bronchiolitis in Scotland, 2001-2016: A National Retrospective Observational Study.
Alexandria Chung,Rachel M Reeves,Harish Nair,Harry Campbell,Resceu Investigators,You Li,Maarten van Wijhe,Thea Kølsen Fischer,Lone Simonsen,Ramona Trebbien,Sabine Tong,Mathieu Bangert,Clarisse Demont,Toni Lehtonen,Terho Heikkinen,Anne C. Teirlinck,Michiel van Boven,Wim van der Hoek,Nicoline A.T. van der Maas,Adam Meijer,Liliana Vazquez Fernandez,Håkon Bøås,Terese Bekkevold,Elmira Flem,Luca Stona,Irene Speltra,Carlo Giaquinto,Arnaud Cheret,Amanda J. Leach,Sonia K Stoszek,Philippe Beutels,Louis Bont,Andrew J. Pollard,Peter J. M. Openshaw,Michael E Abram,Kena A. Swanson,Brian Rosen,Eva Molero +37 more
TL;DR: Assessment of temporal trends in bronchiolitis admissions for children under 2 years of age in Scotland by patient characteristics, socioeconomic deprivation, and duration of admission provides baseline epidemiological data to aid policy makers in the strategic planning of preventative interventions.
19
AZD7442 demonstrates prophylactic and therapeutic efficacy in non-human primates and extended half-life in humans
Yueh-Ming Loo,Patrick M. McTamney,Rosalinda H Arends,Robert A. Gasser,Michael E Abram,Anastasia Aksyuk,Seme Diallo,Daniel J Flores,Elizabeth J. Kelly,Kuishu Ren,Richard Roque,Kim Rosenthal,Katie Streicher,Kevin M Tuffy,Nicholas J. Bond,Owen Cornwell,Jerome Bouquet,Lily Cheng,James Dunyak,Yue Huang,Anton I. Rosenbaum,Hanne Andersen,Robert H. Carnahan,James E. Crowe,James E. Crowe,Ana I. Kuehne,Andrew S. Herbert,John M. Dye,Helen Bright,Nicole L. Kallewaard,Menelas N. Pangalos,Mark T. Esser +31 more
TL;DR: AzD7442 as discussed by the authors is a combination of two monoclonal antibodies (mAbs) against SARS-CoV-2, which can prevent and treat COVID-19, and reduce the risk of severe disease and death.
Pango lineage designation and assignment using SARS-CoV-2 spike gene nucleotide sequences
TL;DR: The Pango dynamic nomenclature is a popular system for classifying and naming genetically distinct lineages of SARS-CoV-2, including variants of concern, and is based on the analysis of complete or near-complete virus genomes as discussed by the authors.