Michael D. Freeman
Maastricht University
121 Papers
930 Citations
Michael D. Freeman is an academic researcher from Maastricht University. The author has contributed to research in topics: Poison control & Whiplash. The author has an hindex of 21, co-authored 117 publications. Previous affiliations of Michael D. Freeman include Oregon Health & Science University & Umeå University.
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Papers
•Journal Article
Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells.
Christopher J. Centeno,Dan Busse,John D. Kisiday,Cristin Keohan,Michael D. Freeman,David Karli +5 more
TL;DR: In this article, the mesenchymal stem cells were isolated and cultured ex-vivo from bone marrow aspiration of the iliac crest and then percutaneously injected into the subject's knee with MRI proven degenerative joint disease.
342
The Role of the Lumbar Multifidus in Chronic Low Back Pain: A Review
TL;DR: Muscle training directed at teaching patients to activate their lumbar multifidus muscles is an important feature of any clinical approach to the LBP patient with demonstrated LMM dysfunction or atrophy.
322
A review and methodologic critique of the literature refuting whiplash syndrome.
TL;DR: There is no epidemiologic or scientific basis in the literature for the following statements: whiplash injuries do not lead to chronic pain, rear impact collisions that do not result in vehicle damage are unlikely to cause injury, andWhiplash trauma is biomechanically comparable with common movements of daily living.
177
Regeneration of meniscus cartilage in a knee treated with percutaneously implanted autologous mesenchymal stem cells.
Christopher J. Centeno,Dan Busse,John D. Kisiday,Cristin Keohan,Michael D. Freeman,David Karli +5 more
TL;DR: A review highlighting the developments in cellular and regenerative medicine in the arena mesenchymal stem cell therapy, as well as a case of successful harvest, expansion, and transplant of autologous mesenchyal stem cells into an adult human knee that resulted in an increase in meniscal cartilage volume.
166
Treatment of lumbar degenerative disc disease-associated radicular pain with culture-expanded autologous mesenchymal stem cells: a pilot study on safety and efficacy
Christopher J. Centeno,Jason Markle,Ehren Dodson,Ian Stemper,Christopher J. Williams,Matthew Hyzy,Thomas E. Ichim,Michael D. Freeman +7 more
TL;DR: Patients treated with autologous cultured MSCs for lower back pain with radicular symptoms in the setting of DDD reported minor adverse events and significant improvements in pain, function, and overall subjective improvement through 6 years of follow-up.