Michael Bossenz
University of Hamburg
10 Papers
5 Citations
Michael Bossenz is an academic researcher from University of Hamburg. The author has contributed to research in topics: Transcription factor & Ubiquitin ligase. The author has an hindex of 8, co-authored 10 publications. Previous affiliations of Michael Bossenz include Otto-von-Guericke University Magdeburg.
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Papers
Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice
JongDae Shin,Michael Bossenz,Michael Bossenz,Young Min Chung,Hong Ma,Meg Byron,Naoko Taniguchi-Ishigaki,Xiaochun Zhu,Xiaochun Zhu,Baowei Jiao,Lisa L. Hall,Michael R. Green,Michael R. Green,Stephen N. Jones,Irm Hermans-Borgmeyer,Jeanne B. Lawrence,Ingolf Bach +16 more
TL;DR: It is shown that the maternal transmission of the mutant X chromosome (Δm) leads to lethality in female embryos as a result of defective imprinted XCI, and evidence is provided that in Δm female embryos the initial formation of Xist clouds and Xp silencing are inhibited.
The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones
Baris Tursun,Anne Schlüter,Marvin A. Peters,Birte Viehweger,Heather P. Ostendorff,Juliana Soosairajah,Alexander Drung,Alexander Drung,Michael Bossenz,Steven A. Johnsen,Michaela Schweizer,Ora Bernard,Ingolf Bach,Ingolf Bach +13 more
TL;DR: Results assign a specific role for Rnf6 in the control of cellular LIMK1 concentrations and indicate a new function for the ubiquitin/proteasome system in regulating local growth cone actin dynamics.
RLIM is dispensable for X-chromosome inactivation in the mouse embryonic epiblast.
JongDae Shin,Mary C. Wallingford,Judith Gallant,Chelsea Marcho,Baowei Jiao,Meg Byron,Michael Bossenz,Jeanne B. Lawrence,Stephen N. Jones,Jesse Mager,Ingolf Bach +10 more
TL;DR: It is demonstrated that female cells lacking RLIM from pre-implantation stages onwards show hallmarks of XCI, including Xist clouds and H3K27me3 foci, and have full embryogenic potential, indicating that in mice an RLIM-independent mechanism activates Xist in the embryo proper.
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Multiple functions of LIM domain-binding CLIM/NLI/Ldb cofactors during zebrafish development
Thomas Becker,Heather P. Ostendorff,Michael Bossenz,Anne Schlüter,Catherina G. Becker,Reto I. Peirano,Ingolf Bach +6 more
TL;DR: It is shown that CLIM cofactors are widely expressed during zebrafish development with high protein levels in specific neuronal cell types where LIM-HD proteins of the Isl class are synthesized.
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Comparing protein stabilities during zebrafish embryogenesis.
Thomas Becker,Michael Bossenz,Baris Tursun,Anne Schlüter,Marvin A. Peters,Catherina G. Becker,Heather P. Ostendorff,Ingolf Bach +7 more
- 01 Jan 2003
TL;DR: This work presents a convenient method that allows the analysis and comparison of protein stabilities during embryogenesis using early zebrafish development as a model system and found that the protein stability of the ubiquitin ligase RLIM was much shorter when compared to a protein consisting of a Myc epitope-tag and a nuclear localization domain.