Michael B. Henschke
Ames Research Center
4 Papers
Michael B. Henschke is an academic researcher from Ames Research Center. The author has contributed to research in topics: Spaceflight & Mutant. The author has an hindex of 4, co-authored 4 publications.
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Papers
The O/OREOS Mission: First Science Data from the Space Environment Survivability of Living Organisms (SESLO) Payload
Wayne L. Nicholson,Antonio J. Ricco,Elwood Agasid,Christopher Beasley,Millan Diaz-Aguado,Pascale Ehrenfreund,Charles Friedericks,Shakib Ghassemieh,Michael B. Henschke,John W. Hines,Christopher Kitts,Ed Luzzi,Diana Ly,Nghia Mai,Rocco L. Mancinelli,Mike McIntyre,Giovanni Minelli,Michael A. Neumann,Macarena Parra,Matthew Piccini,R. Mike Rasay,Robert Ricks,O. Santos,Aaron Schooley,David Squires,Linda Timucin,Bruce Yost,Anthony Young +27 more
TL;DR: The first telemetered spaceflight science results from the orbiting SESLO experiment are reported, executed by one of the two 10 cm cube-format payloads aboard the O/OREOS free-flying nanosatellite.
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Payload hardware and experimental protocol development to enable future testing of the effect of space microgravity on the resistance to gentamicin of uropathogenic Escherichia coli and its σ s -deficient mutant
Abdul Matin,Jonathan Wang,M. Keyhan,Rachna Singh,Michael R. Benoit,Macarena Parra,Michael R. Padgen,Antonio J. Ricco,Matthew Chin,Charlie Friedericks,Tori N. Chinn,Aaron Cohen,Michael B. Henschke,Timothy V. Snyder,Matthew P. Lera,Shannon S. Ross,Christina M. Mayberry,Sungshin Choi,Diana T. Wu,Ming X. Tan,Travis Boone,Christopher C. Beasley,Matthew Piccini,Stevan Spremo +23 more
TL;DR: Preparations to examine UPEC's Gm sensitivity during spaceflight using the E. coli Anti-Microbial Satellite (EcAMSat) as a free-flying "nanosatellite" in low Earth orbit are reported and results should clarify inconsistencies from previous space experiments on bacterial antibiotic sensitivity and other issues.
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EcAMSat spaceflight measurements of the role of σs in antibiotic resistance of stationary phase Escherichia coli in microgravity.
Michael R. Padgen,Matthew P. Lera,Macarena Parra,Antonio J. Ricco,Matthew Chin,Tori N. Chinn,Aaron Cohen,Charlie Friedericks,Michael B. Henschke,Timothy V. Snyder,Stevan Spremo,Jing-Hung Wang,A.C. Matin +12 more
TL;DR: The EcAMSat experiment concludes that the rpoS gene and its downstream products are important therapeutic targets for treating bacterial infections in space, much as they are on the ground.
PharmaSat: drug dose response in microgravity from a free-flying integrated biofluidic/optical culture-and-analysis satellite
Antonio J. Ricco,Macarena Parra,David W. Niesel,Matthew Piccini,Diana Ly,Michael R. McGinnis,Andrzej Kudlicki,John W. Hines,Linda Timucin,C. Beasley,Robert Ricks,Mike McIntyre,Charlie Friedericks,Michael B. Henschke,Ricky Leung,Millan Diaz-Aguado,Christopher Kitts,Ignacio Mas,Mike Rasay,Elwood Agasid,Ed Luzzi,Karolyn Ronzano,David Squires,Bruce Yost +23 more
- 10 Feb 2011
TL;DR: The PharmaSat nanosatellite as mentioned in this paper is a 5.1-kg free flying "nanosatellite" that supported microbial growth in 48 microfluidic wells, dosed microbes with multiple concentrations of a pharmaceutical agent, and monitored microbial growth and metabolic activity using a dedicated 3-color optical absorbance system at each microwell.