Miao Wang
9 Papers
21 Citations
Miao Wang is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 3 publications.
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Papers
G3BP1 promotes DNA binding and activation of cGAS.
Zhao-Shan Liu,Hong Cai,Wen Xue,Miao Wang,Tian Xia,Wan-Jin Li,Jia-Qing Xing,Ming Zhao,Yi-Jiao Huang,Shuai Chen,Wu Shengming,Xinzheng Wang,Xin Liu,Xue Pang,Zi-Yu Zhang,Tingting Li,Jiang Dai,Fangting Dong,Qing Xia,Ai-Ling Li,Tao Zhou,Zheng-gang Liu,Xue-Min Zhang,Li Tao +23 more
TL;DR: It is reported that GTPase-activating protein SH3 domain–binding protein 1 (G3BP1) is critical for DNA sensing and efficient activation of cGAS, a key sensor responsible for cytosolic DNA detection and EGCG-mediated inhibition of G3 BP1 provides a potential treatment forcGAS-related autoimmune diseases.
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GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein.
Ming Zhao,Yu Yu,Li-Ming Sun,Jia-Qing Xing,Tingting Li,Yunkai Zhu,Miao Wang,Yin Yu,Wen Xue,Tian Xia,Hong Cai,Qiu-Ying Han,Xiaoyao Yin,Wei-Hua Li,Ai-Ling Li,Jiuwei Cui,Zhenghong Yuan,Rong Zhang,Tao Zhou,Xue-Min Zhang,Tao Li +20 more
TL;DR: Wang et al. as mentioned in this paper reported that RNA triggers the liquid-liquid phase separation (LLPS) of the SARS-CoV-2 nucleocapsid protein, N.
Molecular basis of broad neutralization against SARS-CoV-2 variants including Omicron by a human antibody
Bin Ju,Qingbing Zheng,Huimin Guo,Qing Fan,Tingting Li,Shuo Song,Hui Sun,Senlin Shen,Xinrong Zhou,Lin Cheng,Wenhui Xue,Lingyan Cui,Bing Zhou,Xiangyang Ge,Haiyan Wang,Miao Wang,Shaowei Li,Ningshao Xia,Zheng Zhang +18 more
TL;DR: It is found that Omicron variant is significantly more evasive than Beta and Mu variants, and BnAbs targeting more conserved epitopes among variants will continue to play a key role in pandemic control and prevention.
A key F27I substitution within HCDR1 facilitates the rapid maturation of P2C-1F11-like neutralizing antibodies in a SARS-CoV-2-infected donor
Miao Wang,Qing Fan,Bing Zhou,Haocheng Ye,Senlin Shen,Jiazhen Yu,Lin Cheng,Xiangyang Ge,Bin Ju,Zheng Zhang +9 more
TL;DR: In this paper , the authors explore the dynamics of antibody repertoire in a SARS-CoV-2-infected donor, from whom the potent and broad nAb P2C-1F11 (the parent version of Brii-196) was previously isolated.
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Predictive value of electrocardiographic markers in children with dilated cardiomyopathy
TL;DR: The prognostic value of electrocardiographic markers in children with DCM is reviewed, which can lead to serious consequences such as malign arrhythmia, sudden death, heart failure, and thromboembolism.
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