Mi-Ok Sim
Sunchon National University
20 Papers
54 Citations
Mi-Ok Sim is an academic researcher from Sunchon National University. The author has contributed to research in topics: Chemistry & Insulin resistance. The author has an hindex of 8, co-authored 20 publications.
Chat about Author
Papers
Anti-steatotic and anti-inflammatory roles of syringic acid in high-fat diet-induced obese mice
TL;DR: Dietary SA possesses anti-obesity, anti-inflammatory and anti-steatotic effects via the regulation of lipid metabolic and inflammatory genes and is likely to be a new natural therapeutic agent for obesity or non-alcoholic liver disease.
115
Long-term supplementation of umbelliferone and 4-methylumbelliferone alleviates high-fat diet induced hypertriglyceridemia and hyperglycemia in mice
TL;DR: UF and mUF similarly ameliorate hypertriglyceridemia and hyperglycemia partly by modulating hepatic lipid metabolism and the antioxidant defense system along with increasing adiponectin levels, as well as improving glucose intolerance and hepatic steatosis in the high-fat fed mice.
45
Dietary umbelliferone attenuates alcohol-induced fatty liver via regulation of PPARα and SREBP-1c in rats.
TL;DR: Results indicated that UF attenuated alcoholic steatosis through down- Regulation of SREBP-1c-mediated lipogenesis and up-regulation of PPARα-mediated fatty acid oxidation may provide a promising natural therapeutic strategy against alcoholic fatty liver.
32
Beneficial Effects of Cynaroside on Cisplatin-Induced Kidney Injury In Vitro and In Vivo.
Jong-Hyun Nho,Ho-Kyung Jung,Mu-Jin Lee,Ji-Hun Jang,Mi-Ok Sim,Da-Eun Jeong,Hyun-Woo Cho,Jong-Choon Kim +7 more
TL;DR: Investigation of the beneficial effect of cynaroside on cisplatin-induced kidney injury using HK-2 cell (human proximal tubule cell line) and an animal model indicated that cynarOSide could be used for improving cisplin-induced side effects.
Long-term supplementation of esculetin ameliorates hepatosteatosis and insulin resistance partly by activating AdipoR2–AMPK pathway in diet-induced obese mice
TL;DR: It is suggested that esculetin supplementation has beneficial effects on hepatosteatosis and insulin resistance in HFD-induced obese mice, partly via activation of the AdiopR2–AMPK pathway.
26