Merve Yonar
Brigham and Women's Hospital
4 Papers
1 Citations
Merve Yonar is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Lymph & Kidney. The author has an hindex of 2, co-authored 4 publications.
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Papers
Targeting antigen-presenting cells by anti–PD-1 nanoparticles augments antitumor immunity
Farideh Ordikhani,Mayuko Uehara,Vivek Kasinath,Li Dai,Siawosh K. Eskandari,Baharak Bahmani,Merve Yonar,Jamil Azzi,Yousef Haik,Peter T. Sage,George F. Murphy,Nasim Annabi,Tobias Schatton,Indira Guleria,Reza Abdi +14 more
TL;DR: It is found that anti-PD-1 NPs undergo internalization by DCs in the spleen, leading to their maturation and the subsequent activation of T cells, which improves the antitumor effect of this agent in the B16-F10 murine melanoma model.
Cellular Mechanisms of Rejection of Optic and Sciatic Nerve Transplants: An Observational Study.
Merve Yonar,Mayuko Uehara,Naima Banouni,Vivek Kasinath,Xiaofei Li,Liwei Jiang,Jing Zhao,Fengfeng Bei,Su Ryon Shin,Curtis L. Cetrulo,Nasim Annabi,Reza Abdi +11 more
TL;DR: These findings establish the feasibility of a preclinical allogenic nerve transplantation model for understanding the cellular mechanisms behind the rejection of peripheral and optic nerves and provide the basis for future testing of directed, high-intensity immunosuppression in these mice.
Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival
Mayuko Uehara,Xiaofei Li,Amir Sheikhi,Nooshin Zandi,Nooshin Zandi,Nooshin Zandi,Brian Walker,Brian Walker,Bahram Saleh,Naima Banouni,Liwei Jiang,Farideh Ordikhani,Li Dai,Merve Yonar,Ishaan Vohra,Vivek Kasinath,Dennis P. Orgill,Ali Khademhosseini,Nasim Annabi,Reza Abdi +19 more
TL;DR: Using a highly stringent skin transplant model, the GelMA/anti- IL-6 IMB was far superior to systemic anti-IL-6 receptor treatment in prolonging skin allograft survival and its potential utility in treating patients with severe burns.
Urine podoplanin heralds the onset of ischemia-reperfusion injury of the kidney
Vivek Kasinath,Osman A. Yilmam,Mayuko Uehara,Merve Yonar,Liwei Jiang,Xiaofei Li,Weiliang Qiu,Siawosh K. Eskandari,Takaharu Ichimura,Reza Abdi +9 more
TL;DR: The findings indicate that the measurement of urine podoplanin harbors promising potential for use as a novel biomarker for the early detection of ischemia-reperfusion injury of the kidney.