Meng Sun
6 Papers
Meng Sun is an academic researcher. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 1, co-authored 4 publications.
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Papers
Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trapping strategy.
Longfa Kou,Huirong Huang,Ying Zhong Tang,Meng Sun,Yingtao Li,Jianing Wu,Shimin Zheng,Xin Zhao,Daosen Chen,Zucheng Luo,Xiaolei Zhang,Qing Yao,Ruijie Chen +12 more
TL;DR: In this paper , a novel opsonization trapping strategy for osteoarthritis drug delivery and treatment is proposed, which transforms a normal nanoparticle into an opsonized attractant to target and regulate macrophage polarization.
52
Bilirubin ameliorates osteoarthritis via activating Nrf2/HO-1 pathway and suppressing NF-κB signalling.
TL;DR: Bilirubin ameliorates osteoarthritis by activating Nrf2/HO-1 pathway and suppressing NF-κB signalling, protecting chondrocytes from oxidative stress and inflammation.
9
A Biomimetic Nanoparticle Exerting Protection Against Acute Liver Failure by Suppressing CYP2E1 Activity and Scavenging Excessive ROS.
Qing Yao,Ying Zhong Tang,Zewei Jiang,Shiming Zheng,Meng Sun,Ruijie Lu,Tuyue Sun,Huirong Huang,Xinyu Jiang,GuangYong Lin,Longfa Kou,Ruijie Chen +11 more
TL;DR: In this article , a carrier-free and bilirubin dotted nanoparticle (B/BG@N) was developed to reduce the production of NAPQI and ROS.
9
Ultraviolet B radiation-induced JPH203-loaded keratinocyte extracellular vesicles exert etiological interventions for psoriasis therapy.
Xinyu Jiang,Zewei Jiang,Shuqi Huang,Pengfei Mao,Linyi Zhang,Minghui Wang,Jinyao Ye,Lining Sun,Meng Sun,Ruijie Lu,Tuyue Sun,Huixiang Sheng,Xin Zhao,Aimin Cai,Xinhua Ma,Qing Yao,GuangYong Lin,Ruijie Chen,Longfa Kou +18 more
TL;DR: This study shows that J@EV exerts therapeutic efficacy for psoriasis by suppressing LAT1-mTOR involved keratinocyte hyperproliferation and Th17 expansion, as well as inhibiting IL-1-NF-κB mediated inflammation, representing a novel and promising strategy for Psoriasis therapy.
6
Carbidopa suppresses estrogen receptor-positive breast cancer via AhR-mediated proteasomal degradation of ERα
Zhiwei Chen,Xing Xia,Heyan Chen,Huirong Huang,Xingsi An,Meng Sun,Qing Yao,Kwon Seop Kim,Hailin Zhang,Maoping Chu,Ruijie Chen,Yangzom D. Bhutia,Vadivel Ganapathy,Longfa Kou +13 more
TL;DR: Carbidopa has therapeutic potential for ER-positive breast cancer either as a single agent or in combination with other standard chemotherapies as discussed by the authors , and the effects of carbidopa on breast cancer were evaluated in cell culture and in mouse xenografts.