Melissa Tay
University Health System
5 Papers
40 Citations
Melissa Tay is an academic researcher from University Health System. The author has contributed to research in topics: Nephrectomy & Renal function. The author has an hindex of 4, co-authored 5 publications.
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Papers
Tryptophan-kynurenine ratio as a biomarker of bladder cancer.
Sze Han Lee,Ratha Mahendran,Sin Mun Tham,Thomas Paulraj Thamboo,Billy Jianhao Chionh,Yi Xin Lim,Woon Tsang,Qing Hui Wu,Jun Yang Chia,Melissa Tay,Benjamin Yen Seow Goh,Kelven Weijing Chen,Jeane Zepeda Mallari,Revathi Periaswami,Lata Raman,Shoa Nian Choo,Dorinda Yan Qin Kioh,Edmund Chiong,Edmund Chiong,Kesavan Esuvaranathan,Kesavan Esuvaranathan,Eric Chun Yong Chan +21 more
TL;DR: To investigate plasma and urinary kynurenine (KYN)–tryptophan (TRP) ratios in bladder cancer, expression of indoleamine 2,3‐dioxygenase 1 (IDO1) in relation to tryptophan 2, 3‐diosgenase (TDO2) in bladder tumour, and the correlation of KYN–TRP ratio with bladder tumours burden are investigated.
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High R.E.N.A.L. Nephrometry scores are associated with pathologic upstaging of clinical T1 renal-cell carcinomas in radical nephrectomy specimens: implications for nephron-sparing surgery.
Melissa Tay,Thomas Paulraj Thamboo,Fiona Mei Wen Wu,Chen Zhaojin,Tai Bee Choo,Lata Ramaan,Ho Yee Tiong +6 more
TL;DR: This study aimed to identify the association of preoperative clinical and tumor features assessed by the RNS with pathologic upstaging of clinical T1 renal-cell carcinomas (RCCs) in complete en bloc radical nephrectomy (RN) specimens.
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•Journal Article
Postoperative risk of chronic kidney disease in radical nephrectomy and donor nephrectomy patients: a comparison and analysis of predictive factors.
Fiona Mei Wen Wu,Melissa Tay,Zhaojin Chen,Bee Choo Tai,Lincoln Guan Lim Tan,Lata Raman,Ho Yee Tiong +6 more
TL;DR: RN is not an independent predictive factor for CKD but the lower baseline renal function in RN patients significantly accelerates renal senescence in the uninephrectomy state.
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Preoperative Renal Volume: A Surrogate Measure for Radical Nephrectomy-Induced Chronic Kidney Disease
Fiona Mei Wen Wu,Melissa Tay,Bee Choo Tai,Zhaojin Chen,Lincoln Gl Tan,Benjamin Yen Seow Goh,Lata Raman,Ho Yee Tiong +7 more
TL;DR: Normal kidney parenchymal volume and preoperative eGFR are independent predictive factors for postoperative CKD after RN and may represent renal reserve for both surgically and medically induced CKD, respectively.
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Mp30-10 high r.e.n.a.l nephrometry scores (rns) are associated with pathological upstaging of clinical t1 renal cell carcinomas (rcc) in radical nephrectomy (rn) specimens: implications for nephron-sparing surgery.
TL;DR: RCCs that are p53 positive, with a high Ki67 positivity rate and high tumor grade, have the potential for fast growth and should be extirpated early.
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