Melissa A. Vanover
University of California, Davis
14 Papers
37 Citations
Melissa A. Vanover is an academic researcher from University of California, Davis. The author has contributed to research in topics: Fetal surgery & Medicine. The author has an hindex of 9, co-authored 13 publications.
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Papers
Fetal Surgery for Myelomeningocele: A Systematic Review and Meta-Analysis of Outcomes in Fetoscopic versus Open Repair.
TL;DR: Fetoscopic repair is a promising alternative to open fetal MMC repair with a lower risk of uterine dehiscence; however, fetoscopic techniques should be optimized to overcome the high rate of dehISCence and leakage at the M MC repair site.
Placental mesenchymal stromal cells seeded on clinical grade extracellular matrix improve ambulation in ovine myelomeningocele
Sandra K Kabagambe,Benjamin A. Keller,James Becker,Laura F. Goodman,Christopher D. Pivetti,Lee Lankford,Karen Chung,Chelsey Lee,Y. Julia Chen,Priyadarsini Kumar,Melissa A. Vanover,Aijun Wang,Diana L. Farmer +12 more
TL;DR: Fetal repair of MMC with PMSCs seeded on SIS-ECM improves hindlimb motor function in lambs, but adding PM SCs improves the lamb's ability to walk and increases large neuron density.
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Potential clinical applications of placental stem cells for use in fetal therapy of birth defects
TL;DR: Though much work still needs to be done, placental stem cells are a promising therapeutic agent for fetal intervention for congenital disease with potential for in utero treatment of congenital disorders.
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Spinal Angulation: A Limitation of the Fetal Lamb Model of Myelomeningocele.
Melissa A. Vanover,Christopher D. Pivetti,Laura A. Galganski,Priyadarsini Kumar,Lee Lankford,Douglas J. Rowland,Zachary J. Paxton,Bailey Deal,Aijun Wang,Diana L. Farmer +9 more
TL;DR: Surgical creation of fetal MMC leads to varying severity of spinal angulation in the ovine model, which affects postnatal functional outcomes, and postnatal assessment of spinalAngulation aids in standardization of the surgical model of Fetal MMC repair.
New directions in fetal surgery for myelomeningocele
TL;DR: Long-term follow-up of ambulatory status, executive functioning, and urological outcomes is needed to determine the durable effects of fetal MMC repair on mobility, functional independence, and the prevalence of renal insufficiency in patients with MMC who survive to adulthood.
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