Mei Wang
Nanjing Medical University
11 Papers
4 Citations
Mei Wang is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Stem cell & Glial cell line-derived neurotrophic factor. The author has an hindex of 6, co-authored 10 publications.
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Papers
Reprogramming of Meiotic Chromatin Architecture during Spermatogenesis
Yao Wang,Hanben Wang,Yu Zhang,Zhenhai Du,Wei Si,Suixing Fan,Dongdong Qin,Mei Wang,Yanchao Duan,Lufan Li,Yuying Jiao,Yuanyuan Li,Qiujun Wang,Qinghua Shi,Xin Wu,Wei Xie +15 more
TL;DR: Interestingly, it is found that topologically associating domains (TADs) undergo dissolution and reestablishment in spermatogenesis in rhesus monkey using low-input Hi-C, suggesting that the synaptonemal complex may restrict TADs and promote local compartments.
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A long non-coding RNA interacts with Gfra1 and maintains survival of mouse spermatogonial stem cells
TL;DR: The data provide the first evidence that long non-coding RNAs (lncRNAs) regulate SSC fate, and lncRNA033862 knockdown severely impairs SSC survival and their capacity to repopulate recipient testes in a transplantation assay.
The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation
Min Wang,Yueshuai Guo,Mei Wang,Tao Zhou,Yuanyuan Xue,Guihua Du,Xiang Wei,Jing Wang,Lin Qi,Hao Zhang,Lufan Li,Lan Ye,Xuejiang Guo,Xin Wu +13 more
TL;DR: These findings implicate previously undescribed signaling networks in governing fate decision of SPCs, which is essential for the understanding of spermatogenesis and of potential consequences of pathogenic insult for male infertility.
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mRBPome capture identifies the RNA-binding protein TRIM71, an essential regulator of spermatogonial differentiation.
Guihua Du,Guihua Du,Xinrui Wang,Mengcheng Luo,Mengcheng Luo,Weiya Xu,Tao Zhou,Mei Wang,Luping Yu,Lufan Li,Li'e Cai,P. Jeremy Wang,John Zhong Li,Jon M. Oatley,Xin Wu +14 more
TL;DR: Findings demonstrate a key role of the RBP system in regulation of the spermatogenic lineage and may provide clues about the influence of RBPs on the biology of progenitor cell populations in other lineages.
Differential regulation of spermatogenic process by Lkb1 isoforms in mouse testis.
Feifei Kong,Mei Wang,Xiaojing Huang,Qiuling Yue,Xiang Wei,Xiaowei Dou,Xiaoxu Peng,Yuanyuan Jia,Ke Zheng,Tinghe Wu,Jun Yan,Jing Li +11 more
TL;DR: Different roles of LKB1 isoforms in spermatogenesis with Lkb1L directing SPCs maintenance, and L kb1L and L KB1S coordinately regulating sperMatid differentiation are supported.