Meghan K. Eberhardt
University of California, Davis
14 Papers
72 Citations
Meghan K. Eberhardt is an academic researcher from University of California, Davis. The author has contributed to research in topics: Immune system & Antibody. The author has an hindex of 11, co-authored 14 publications. Previous affiliations of Meghan K. Eberhardt include California National Primate Research Center & University of California.
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Papers
Evaluation of recombinant modified vaccinia Ankara virus-based rhesus cytomegalovirus vaccines in rhesus macaques.
Yujuan Yue,Zhongde Wang,Kristina Abel,Jinliang Li,Lisa Strelow,Angelo Mandarino,Meghan K. Eberhardt,Kimberli A. Schmidt,Don J. Diamond,Peter A. Barry,Peter A. Barry +10 more
TL;DR: This study demonstrates the immunogenicity and protective efficacy of rMVA-based RhCMV sub unit vaccines in a primate host and warrants further investigation to improve the efficacy of subunit vaccines against CMV.
The interplay between immune maturation, age, chronic viral infection and environment
Kristie L. Oxford,Myra Grace Dela Pena-Ponce,Kara Jensen,Meghan K. Eberhardt,Abigail Spinner,Koen K. A. Van Rompay,Joseph Rigdon,Katie R. Mollan,Viswanathan V Krishnan,Michael G. Hudgens,Peter A. Barry,Peter A. Barry,Kristina De Paris +12 more
TL;DR: The data validate rhesus macaques as a relevant animal model to study how chronic viral infections modulate host immunity and impact immunosenescence and could identify important mechanisms associated with inflammaging and thereby lead to new therapies promoting healthy aging in humans.
Design and Analysis of Rhesus Cytomegalovirus IL-10 Mutants as a Model for Novel Vaccines against Human Cytomegalovirus
TL;DR: The results provide the methodology for targeting CMVIL-10 in vaccine, and therapeutic strategies, to nullify HCMV's ability to skew innate and adaptive immunity, disseminate from the site of primary mucosal infection, and establish a lifelong persistent infection.
Host Immune Responses to a Viral Immune Modulating Protein: Immunogenicity of Viral Interleukin-10 in Rhesus Cytomegalovirus-Infected Rhesus Macaques
Meghan K. Eberhardt,W. L. William Chang,Naomi J. Logsdon,Yujuan Yue,Mark R. Walter,Peter A. Barry,Peter A. Barry +6 more
TL;DR: This study demonstrates that rhcmVIL-10, as a surrogate for cmvIL- 10, is a viable vaccine candidate because it is highly immunogenic during natural RhCMV infection, and neutralizing antibodies to rhcmv IL-10 do not cross-react with rhesus cil-10.
Suspected Exposure to Filoviruses Among People Contacting Wildlife in Southwestern Uganda.
Tierra Smiley Evans,Leonard Tutaryebwa,Kirsten V. K. Gilardi,Peter A. Barry,Andrea Marzi,Meghan K. Eberhardt,Benard Ssebide,Michael R. Cranfield,Obed Mugisha,Emmanuel Mugisha,Scott Kellermann,Jonna A. K. Mazet,Christine K. Johnson +12 more
TL;DR: Touching duikers was the most significant risk factor associated with EBOV seropositivity, while hunting primates and touching and/or eating cane rats were significant risk factors for SUDV seripositivity.