Megha Padi
University of Arizona
36 Papers
99 Citations
Megha Padi is an academic researcher from University of Arizona. The author has contributed to research in topics: Gene & Gene regulatory network. The author has an hindex of 13, co-authored 29 publications. Previous affiliations of Megha Padi include Harvard University.
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Papers
Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks
TL;DR: The approach yields high confidence ranked target gene maps for TP53, DREAM, MMB-FOXM1 and RB-E2F and enables prediction and distinction of CC regulation.
Effects of ursodeoxycholic acid on the gut microbiome and colorectal adenoma development.
Talima Pearson,J. Gregory Caporaso,Monica Yellowhair,Nicholas A. Bokulich,Megha Padi,Denise J. Roe,Betsy C. Wertheim,Mark Linhart,Jessica A. Martinez,Cherae Bilagody,Heidie Hornstra,David S. Alberts,Peter Lance,Patricia A. Thompson,Patricia A. Thompson +14 more
TL;DR: Daily UDCA use modestly influences the relative abundance of microbial species in stool and affects the microbial network composition with suggestive evidence for sex‐specific effects of UDCA on stool microbial community composition as a modifier of colorectal adenoma risk.
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Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning
Adam W. Watson,Adam D. Grant,Sara S. Parker,Samantha M. Hill,Michael B. Whalen,Jayati Chakrabarti,Michael W. Harman,Mackenzie R. Roman,Brittany L. Forte,Cody C. Gowan,Raul Castro-Portuguez,Lindsey K. Stolze,Christian Franck,Darren A. Cusanovich,Yana Zavros,Megha Padi,Casey E. Romanoski,Ghassan Mouneimne +17 more
TL;DR: In this article, a multigenic score of mechanical conditioning (MeCo) was found associated with bone metastasis in patients with breast cancer, and the authors demonstrated that mechanical conditioning maintenance can be simulated, repressed, or extended, with corresponding changes in bone metastatic potential.
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Canonical NF-κB Activation Is Essential for Epstein-Barr Virus Latent Membrane Protein 1 TES2/CTAR2 Gene Regulation
Benjamin E. Gewurz,Jessica C. Mar,Megha Padi,Bo Zhao,Nicholas P. Shinners,Kaoru Takasaki,Edward Bedoya,James Y. Zou,Ellen Cahir-McFarland,John Quackenbush,Elliott Kieff +10 more
TL;DR: Gene set enrichment analyses found LMP1 TES2-upregulated genes to be significantly enriched for pathways in cancer, B- and T-cell receptor signaling, and Toll-like receptor signaling.
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Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation
Christian Berrios,Megha Padi,Donglim Esther Park,Vadim Molla,Jingwei Cheng,Soo Mi Lee,Gregory Stephanopoulos,John Quackenbush,James A. DeCaprio,Mark A. Keibler +9 more
- 01 Nov 2016
TL;DR: In this paper, the authors performed transcriptome analysis of normal human fibroblasts with inducible expression of small tumor antigen (ST) to gain insight into cellular perturbations induced by MCPyV ST.
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