Megan E. Hoerrner
University of Delaware
6 Papers
8 Citations
Megan E. Hoerrner is an academic researcher from University of Delaware. The author has contributed to research in topics: Pyridinium & Allylic rearrangement. The author has an hindex of 4, co-authored 6 publications. Previous affiliations of Megan E. Hoerrner include University of Richmond.
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Papers
Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides
Jennie Liao,Corey H. Basch,Megan E. Hoerrner,Michael R. Talley,Brian P. Boscoe,Joseph W. Tucker,Michelle R. Garnsey,Mary P. Watson +7 more
TL;DR: A nickel-catalyzed reductive cross-coupling of alkylpyridinium salts and aryl bromides has been developed using Mn as the reductant, and mechanisms indicate the formation of an alkyl radical.
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Nickel-Catalyzed Synthesis of Dialkyl Ketones from the Coupling of N-Alkyl Pyridinium Salts with Activated Carboxylic Acids.
TL;DR: This approach is capable of coupling diverse substrates, including pharmaceutical intermediates, to rapidly form complex ketones and has broad scope, as demonstrated by the synthesis of 35 different ketones bearing a wide variety of functional groups with an average yield of 60 ± 16%.
121
Deaminative Arylation of Amino Acid-derived Pyridinium Salts.
TL;DR: A Suzuki-Miyaura cross-coupling of α-pyridinium esters and arylboroxines has been developed and Mechanistic studies support an alkyl radical intermediate, similar to other cross-Couplings of alkylpyrid inium salts.
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Stereospecific, Nickel-Catalyzed Suzuki–Miyaura Cross-Coupling of Allylic Pivalates To Deliver Quaternary Stereocenters
TL;DR: A stereospecific, nickel-catalyzed cross-coupling of allylic pivalates with arylboroxines to deliver products equipped with quaternary stereocenters and internal alkenes was developed.
29
Formyl Group Activation of a Bromopyrrole Ester in Suzuki Cross-Coupling Reactions: Application to a Formal Synthesis of Polycitone A and B and Polycitrin A
John T. Gupton,Nakul Telang,Michael Wormald,Kristin Lescalleet,Jon Patteson,Will Curry,Andrew Harrison,Megan E. Hoerrner,John Sobieski,Michael Kimmel,Emily J. Kluball,Thomas Perry +11 more
TL;DR: A new pyrrole building block is described, which allows for the regiospecific synthesis of 2, 3,5-trisubstituted pyrroles and 2,3,4, 5- tetrasubstItuted p Pyrroles.
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