Maxime Parent

TL;DR: P positron emission tomography evidence is provided that activation of astrocytic glutamate transport via the excitatory amino acid transporter GLT-1 triggers widespread but graded glucose uptake in the rodent brain.

TL;DR: It is found that Aβ aggregation within the brain’s default mode network leads to regional hypometabolism in distant but functionally connected brain regions, suggesting a model in which distant Aβ induces regional metabolic vulnerability, whereas the interaction between local Aβ with a vulnerable environment drives the clinical progression of dementia.

TL;DR: It is demonstrated that the main receptor for morphine predominantly shapes the so-called reward/aversion circuitry, with major influence on negative affect centers, in mice manipulated by targeted deletion of the Oprm1 gene.

TL;DR: The hypothesis that fluctuations during movement consolidation can be prevented through the use of sumanirole - a highly selective D2 agonist - if administered before raclopride is explored.