Maxim Ratnikov
Genomics Institute of the Novartis Research Foundation
5 Papers
8 Citations
Maxim Ratnikov is an academic researcher from Genomics Institute of the Novartis Research Foundation. The author has contributed to research in topics: Ketone & Chemistry. The author has an hindex of 3, co-authored 5 publications.
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Papers
One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp2-Sp3 Cross-Coupling.
Takaoki Koyanagi,Ananda Herath,Ashley Chong,Maxim Ratnikov,Andrew Valiere,Jim Yuchen Chang,Valentina Molteni,Loren Jon +7 more
TL;DR: This undivided cell one-pot method enables C-C bond formation using inexpensive, benchtop-stable reagents with isolated yields up to 95% with good functional group tolerance, which includes nitrile, ketone, ester, alkene and selectivity over other aromatic halogens.
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An Amphiphilic Polymer-Supported Strategy Enables Chemical Transformations under Anhydrous Conditions for DNA-Encoded Library Synthesis
Yves Ruff,Roberto Martinez,Xavier Pelle,Pierre Nimsgern,Pascale Fille,Maxim Ratnikov,Frederic Berst +6 more
TL;DR: The development of a practical catch-and-release methodology utilizing a cationic, amphiphilic PEG-based polymer to perform chemical transformations on immobilized DNA conjugates under anhydrous conditions is described and the usefulness of this approach is demonstrated.
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Photoinduced Rearrangement of Dienones and Santonin Rerouted by Amines.
TL;DR: The photoinduced rearrangement pathways of simple 2,5-dienones and the natural product santonin were found to be effectively rerouted by amines, giving rise to unprecedented products.
8
An Amphiphilic Polymer-Supported Strategy Enables Chemical Transformations Under Anhydrous Conditions for DNA-Encoded Library Synthesis
Yves Ruff,Roberto Martinez,Xavier Pelle,Pierre Nimsgern,Maxim Ratnikov,Frederic Berst,Pascale Fille +6 more
TL;DR: In this article, a catch-and-release methodology utilizing a cationic,amphiphilic PEG-based polymer to perform chemical transformations on the DNA conjugates under anhydrous conditions is described.
1
Patent
5,6-fused-bicyclic compounds and compositions for the treatment of parasitic diseases
Jiricek Jan,Lerario Isabelle K,Fang Liang,Liu Xiaodong,Valentina Molteni,Advait Nagle,Ng Shuyi Pearly,Maxim Ratnikov,Smith Jeffrey M,Yongping Xie +9 more
- 10 Jan 2020
TL;DR: In this paper, a compound of Formula or a pharmaceutically acceptable salt thereof, and a method for manufacturing the compounds of the invention, and its therapeutic uses are described.
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