Max Ladow

TL;DR: Using chronic two-photon calcium imaging in mice performing random foraging or goal-oriented learning tasks, it is found that vasoactive intestinal polypeptide-expressing (VIP+), disinhibitory INs in hippocampal area CA1 form functional subpopulations defined by their modulation by behavioral states and task demands.

TL;DR: It is found that mossy cells are significantly more active than dentate granule cells in vivo, exhibit spatial tuning during head-fixed spatial navigation, and undergo robust remapping of their spatial representations in response to contextual manipulation.

TL;DR: These results show how the hippocampus encodes, stores and updates learned associations and illuminates the unique contributions of dorsal and ventral hippocampus in the encoding and updating of task-related representations throughout learning.

TL;DR: How the hippocampus encodes, stores, and updates learned associations, and illuminates the unique contributions of dorsal and ventral hippocampus is identified.