Max E. Boeck
University of Washington
6 Papers
Max E. Boeck is an academic researcher from University of Washington. The author has contributed to research in topics: Caenorhabditis elegans & Gene expression profiling. The author has an hindex of 6, co-authored 6 publications.
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Papers
Comparative analysis of the transcriptome across distant species
Mark Gerstein,Joel Rozowsky,Koon-Kiu Yan,Daifeng Wang,Chao Cheng,James B. Brown,James B. Brown,Carrie A. Davis,LaDeana W. Hillier,Cristina Sisu,Jingyi Jessica Li,Jingyi Jessica Li,Baikang Pei,Arif Harmanci,Michael O. Duff,Sarah Djebali,Roger P. Alexander,Burak H. Alver,Raymond K. Auerbach,Kimberly Bell,Peter J. Bickel,Max E. Boeck,Nathan Boley,Nathan Boley,Benjamin W. Booth,Lucy Cherbas,Peter Cherbas,Chao Di,Alexander Dobin,Jorg Drenkow,Brent Ewing,Gang Fang,Megan Fastuca,Elise A. Feingold,Adam Frankish,Guanjun Gao,Peter J. Good,Roderic Guigó,Ann S. Hammonds,Jen Harrow,Roger A. Hoskins,Cédric Howald,Cédric Howald,Long Hu,Haiyan Huang,Tim Hubbard,Tim Hubbard,Chau Huynh,Sonali Jha,Dionna M. Kasper,Masaomi Kato,Thomas C. Kaufman,Robert R. Kitchen,Erik Ladewig,Julien Lagarde,Eric C. Lai,Jing Leng,Zhi Lu,Michael J. MacCoss,Gemma E. May,Gemma E. May,Rebecca McWhirter,Gennifer E. Merrihew,David M. Miller,Ali Mortazavi,Rabi Murad,Brian Oliver,Sara Olson,Peter J. Park,Michael J. Pazin,Norbert Perrimon,Norbert Perrimon,Dmitri D. Pervouchine,Valerie Reinke,Alexandre Reymond,Garrett Robinson,Anastasia Samsonova,Anastasia Samsonova,Gary Saunders,Gary Saunders,Felix Schlesinger,Anurag Sethi,Frank J. Slack,William C. Spencer,Marcus H. Stoiber,Marcus H. Stoiber,Pnina Strasbourger,Andrea Tanzer,Andrea Tanzer,Owen Thompson,Kenneth H. Wan,Guilin Wang,Huaien Wang,Kathie L. Watkins,Jiayu Wen,Kejia Wen,Chenghai Xue,Li Yang,Li Yang,Kevin Y. Yip,Chris Zaleski,Yan Zhang,Henry Zheng,Steven E. Brenner,Brenton R. Graveley,Susan E. Celniker,Thomas R. Gingeras,Robert H. Waterston +107 more
TL;DR: It is found in all three organisms that the gene-expression levels, both coding and non-coding, can be quantitatively predicted from chromatin features at the promoter using a ‘universal model’ based on a single set of organism-independent parameters.
Specific roles for the GATA transcription factors end-1 and end-3 during C. elegans E-lineage development.
TL;DR: The results indicate that end-1 and end-3 have each evolved into genes with unique functions during endoderm development, thatend-3(-) embryos have a delay in the onset of E lineage cell fate and that end.1 has only a partially penetrant ability to activate E lineage fate.
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The time-resolved transcriptome of C. elegans
Max E. Boeck,Chau Huynh,Lou Gevirtzman,Owen Thompson,Guilin Wang,Dionna M. Kasper,Valerie Reinke,LaDeana W. Hillier,Robert H. Waterston +8 more
TL;DR: Detailed RNA-seq data for the nematode Caenorhabditis elegans with high temporal resolution in the embryo as well as representative samples from post-embryonic stages across the life cycle reveal that early and late embryogenesis is accompanied by large numbers of genes changing expression, whereas fewer genes are changing in mid- Embryogenesis.
Multidimensional regulation of gene expression in the C. elegans embryo
John I. Murray,Thomas J. Boyle,Elicia Preston,Elicia Preston,D. Vafeados,Barbara Mericle,Peter Weisdepp,Zhongying Zhao,Zhirong Bao,Zhirong Bao,Max E. Boeck,Robert H. Waterston +11 more
TL;DR: This work quantitatively measured reporter expression of 127 genes, primarily transcription factors, in every cell and with high temporal resolution in C. elegans embryos, providing the first large-scale, digitally based, cellular resolution compendium of gene expression dynamics in live animals.
Automated analysis of embryonic gene expression with cellular resolution in C. elegans.
John I. Murray,Zhirong Bao,Zhirong Bao,Thomas J. Boyle,Max E. Boeck,Barbara Mericle,Thomas J. Nicholas,Zhongying Zhao,Matthew J. Sandel,Robert H. Waterston +9 more
TL;DR: A system that permits the automated analysis of reporter gene expression in Caenorhabditis elegans with cellular resolution continuously during embryogenesis is described and its utility is demonstrated by defining the expression patterns of reporters for several embryonically expressed transcription factors.