Mauro Castagnetta
University of Genoa
12 Papers
29 Citations
Mauro Castagnetta is an academic researcher from University of Genoa. The author has contributed to research in topics: Human leukocyte antigen & Population. The author has an hindex of 5, co-authored 12 publications.
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Papers
First-trimester euploid miscarriages analysed by array-CGH.
Chiara Viaggi,Simona Cavani,Michela Malacarne,F. Floriddia,G. Zerega,C. Baldo,Massimo Mogni,Mauro Castagnetta,G. Piombo,Domenico Coviello,F. Camandona,D. Lijoi,W. Insegno,M. Traversa,Mauro Pierluigi +14 more
TL;DR: This study shows that array-CGH is useful for detecting submicroscopic CNVs and identifying candidate genes which could account for euploid miscarriages, and shows a higher resolution, higher detection rate and overcoming problems of culture failures, maternal contamination and poor chromosome morphology.
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Targeted next-generation sequencing helps to decipher the genetic and phenotypic heterogeneity of hypertrophic cardiomyopathy
Massimiliano Cecconi,Maria Isola Parodi,Francesco Formisano,Paolo Spirito,Camillo Autore,Maria Beatrice Musumeci,Stefano Favale,Cinzia Forleo,Claudio Rapezzi,Elena Biagini,Sabrina Davì,Elisabetta Canepa,Loredana Pennese,Mauro Castagnetta,D. Degiorgio,Domenico A. Coviello +15 more
TL;DR: Co-occuring mutations of genes encoding TTm and non-TTm proteins could explain the wide variability of the HCM phenotype, whereas mutations in genes encoding only the non- TTm proteins are identifiable in patients with a milder HCM status.
5-HT control of ischemia-evoked glutamate efflux from human cerebrocortical slices.
TL;DR: It is concluded that activation of 5-HT receptors of the 5- HT(1A) subtype might help to control glutamate efflux and excitotoxic damage during ischemia in human cerebral cortex and would deserve to be considered in a multipharmacological approach to neuroprotection in brain ischemIA.
16
Galliera Genetic Bank: A DNA and Cell Line Biobank from Patients Affected by Genetic Diseases
C. Baldo,Valeria Viotti,Elisabetta Maioli,Massimo Mogni,Mauro Castagnetta,Simona Cavani,Giuseppe Piombo,Domenico A. Coviello +7 more
TL;DR: The Galliera Genetic Bank is part of the Laboratory of Human Genetics of Galliera Hospital in Genoa and has collected samples from patients affected by genetic diseases since 1983 and stores 10,259 biospecimens and associated data from about 200 genetic disorders.
Biological Age versus Chronological Age in the Prevention of Age Associated Diseases
Gian Andrea Rollandi,Aldo Chiesa,Nicoletta Sacchi,Mauro Castagnetta,Matteo Puntoni,Adriana Amaro,Barbara Banelli,Ulrich Pfeffer +7 more
- 31 Jan 2019
TL;DR: In this paper, the authors developed the hypothesis that age-dependent preventative measures and diagnostic screenings might perform better if the biological age would be used instead of the chronological age for the definition of the population to be included.