Matthew Wook Chang

TL;DR: This study elucidated several factors controlling the antibacterial activity of pristine SWCNTs and it provided an insight in developing strategies that can maximize theSWCNT application potentials while minimizing the health and environment risks.

TL;DR: A modified version of the synthetic genetic system, including a gene encoding an anti-biofilm enzyme, is generated and the engineered probiotic shows in vivo prophylactic and therapeutic activity against P. aeruginosa during gut infection in two animal models (Caenorhabditis elegans and mice).

TL;DR: The development of a synthetic genetic system that enables Escherichia coli to sense and kill a pathogenic Pseudomonas aeruginosa strain through the production and release of pyocin is described, suggesting that E. coli carrying this system may provide a novel synthetic biology‐driven antimicrobial strategy that could potentially be applied to fighting P. aerug inosa and other infectious pathogens.

TL;DR: Engineered commensal microbes that transform natural compounds present in cruciferous vegetables into an anticancer molecule prevent carcinogenesis and promote the regression of colorectal cancer in mice fed with the microbes and the vegetables.