Matthew S. Schechter
University of Chicago
13 Papers
10 Citations
Matthew S. Schechter is an academic researcher from University of Chicago. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 3, co-authored 6 publications. Previous affiliations of Matthew S. Schechter include Max Planck Society.
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Papers
Community-led, integrated, reproducible multi-omics with anvi'o.
A. Murat Eren,Evan Kiefl,Alon Shaiber,Iva Veseli,Samuel E. Miller,Matthew S. Schechter,Isaac Fink,Jessica N. Pan,Mahmoud Yousef,Emily Fogarty,Florian Trigodet,Andrea R. Watson,Özcan C. Esen,Ryan M Moore,Quentin Clayssen,Michael D. Lee,Veronika Kivenson,Elaina D. Graham,Bryan D. Merrill,Antti Karkman,Daniel Blankenberg,Daniel Blankenberg,John M. Eppley,Andreas Sjödin,Jarrod J. Scott,Xabier Vázquez-Campos,Luke J. McKay,Elizabeth A. McDaniel,Sarah L. R. Stevens,Rika E. Anderson,Jessika Fuessel,Antonio Fernandez-Guerra,Lois Maignien,Lois Maignien,Tom O. Delmont,Amy D. Willis +35 more
TL;DR: The workflows designed to enable researchers to interpret data can constrain the biological questions that can be asked as discussed by the authors, but the workflows can also be difficult to adapt to real-world applications.
552
Verrucomicrobia use hundreds of enzymes to digest the algal polysaccharide fucoidan.
Andreas Sichert,Andreas Sichert,Christopher H. Corzett,Christopher H. Corzett,Matthew S. Schechter,Frank Unfried,Stephanie Markert,Doerte Becher,Antonio Fernandez-Guerra,Antonio Fernandez-Guerra,Antonio Fernandez-Guerra,Manuel Liebeke,Thomas Schweder,Martin F. Polz,Martin F. Polz,Jan-Hendrik Hehemann,Jan-Hendrik Hehemann +16 more
TL;DR: Marine metagenomes and microbial genomes show that Verrucomicrobia including ‘Lentimonas’ are abundant and highly specialized degraders of fucoidans and other complex polysaccharides, which was thought to be a recalcitrant source of carbon in the authors' oceans.
252
A cryptic plasmid is among the most numerous genetic elements in the human gut
Emily C. Fogarty,Matthew S. Schechter,Karen Lolans,Madeline L Sheahan,Iva A. Veseli,Ryan M Moore,Evan Kiefl,Thomas Moody,Phoebe A. Rice,Michael Yu,Mark Mimee,Eugene B. Chang,Hans-Joachim Ruscheweyh,Shinichi Sunagawa,Sandra L. Mclellan,Amy D. Willis,Laurie E. Comstock,A. Murat Eren +17 more
TL;DR: Researchers identified a ubiquitous, cryptic plasmid (pBI143) in human gut microbiomes, 14 times more abundant than crAssphage, with strong purifying selection and potential applications in fecal contamination tracking and human colonic inflammatory state monitoring.
23
Light into the darkness: Unifying the known and unknown coding sequence space in microbiome analyses
Chiara Vanni,Chiara Vanni,Matthew S. Schechter,Matthew S. Schechter,Silvia G. Acinas,Albert Barberán,Pier Luigi Buttigieg,Emilio O. Casamayor,Tom O. Delmont,Carlos M. Duarte,A. Murat Eren,A. Murat Eren,Robert D. Finn,Renzo Kottmann,Alex L. Mitchell,Pablo G. Sanchez,Kimmo Sirén,Martin Steinegger,Frank Oliver Glöckner,Antonio Fernandez-Guerra,Antonio Fernandez-Guerra +20 more
TL;DR: With the identification of a target gene of unknown function for antibiotic resistance, it is demonstrated how a contextualized unknown coding sequence space provides a robust framework for the generation of hypotheses that can be used to augment experimental data.
Unifying the global coding sequence space enables the study of genes with unknown function across biomes
Chiara Vanni,Matthew S. Schechter,Silvia G. Acinas,Albert Barberán,Pier Luigi Buttigieg,Emilio O. Casamayor,Tom O. Delmont,Carlos M. Duarte,A. Murat Eren,Robert D. Finn,Renzo Kottmann,Alex L. Mitchell,Pablo Sánchez,Kimmo Sirén,Martin Steinegger,Frank Oliver Glöckner,Antonio Fernandez-Guerra +16 more
TL;DR: By identifying a target gene of unknown function for antibiotic resistance, it is demonstrated how a contextualized unknown coding sequence space enables the generation of hypotheses that can be used to augment experimental data.