Matthew M. Hims
Illumina
17 Papers
18 Citations
Matthew M. Hims is an academic researcher from Illumina. The author has contributed to research in topics: IKBKAP & Exon. The author has an hindex of 14, co-authored 17 publications. Previous affiliations of Matthew M. Hims include St James's University Hospital & University of Leeds.
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Papers
Accurate whole human genome sequencing using reversible terminator chemistry
David R. Bentley,Shankar Balasubramanian,Harold Swerdlow,Harold Swerdlow,Geoffrey Paul Smith,John Milton,John Milton,Clive Gavin Brown,Clive Gavin Brown,Kevin Hall,Dirk J. Evers,Colin Barnes,Colin Barnes,Helen Bignell,Jonathan Mark Boutell,Jason Bryant,Richard J. Carter,R. Keira Cheetham,Anthony J. Cox,Darren James Ellis,Michael R. Flatbush,Niall Anthony Gormley,Sean Humphray,Leslie J. Irving,Mirian S. Karbelashvili,Scott M. Kirk,Heng Li,Xiaohai Liu,Xiaohai Liu,Klaus Maisinger,Lisa Murray,Bojan Obradovic,Tobias William Barr Ost,Michael Lawrence Parkinson,M. R. Pratt,Isabelle Rasolonjatovo,Mark T. Reed,Roberto Rigatti,Chiara Rodighiero,Mark T. Ross,Andrea Sabot,Subramanian V. Sankar,Aylwyn Scally,Gary P. Schroth,Mark Smith,Vincent Peter Smith,Anastassia Spiridou,Peta E. Torrance,Svilen S. Tzonev,Eric Vermaas,Klaudia Walter,Wu Xiaolin,Lu Zhang,Mohammed D. Alam,Carole Anastasi,Ify C. Aniebo,David Mark Dunstan Bailey,Iain R. Bancarz,Saibal Banerjee,Selena G. Barbour,Primo Baybayan,Vincent A. Benoit,Kevin Benson,Claire Bevis,Phillip J. Black,Asha Boodhun,Joe S. Brennan,John Bridgham,Rob C. Brown,Andrew A. Brown,Dale Buermann,Abass A. Bundu,James C. Burrows,Nigel P. Carter,Nestor Castillo,Maria Chiara E. Catenazzi,Simon Chang,R. Neil Cooley,Natasha R. Crake,Olubunmi O. Dada,Konstantinos D. Diakoumakos,Belen Dominguez-Fernandez,David James Earnshaw,David James Earnshaw,Ugonna C. Egbujor,David W. Elmore,Sergey Etchin,Mark R. Ewan,Milan Fedurco,Louise Fraser,Karin Fuentes Fajardo,W. Scott Furey,David George,Kimberley J. Gietzen,Colin P. Goddard,George Stefan Golda,Philip A. Granieri,David E. Green,David L. Gustafson,Nancy F. Hansen,Kevin Harnish,Christian D. Haudenschild,Narinder I. Heyer,Matthew M. Hims,Johnny T. Ho,Adrian Horgan,Katya Hoschler,Steve Hurwitz,Denis V. Ivanov,Maria Q. Johnson,Terena James,T. A. Huw Jones,Gyoung-Dong Kang,Tzvetana H. Kerelska,Alan D. Kersey,Irina Khrebtukova,Alex P. Kindwall,Zoya Kingsbury,Paula Kokko-Gonzales,Anil Kumar,Marc Laurent,Cindy Lawley,Sarah E. Lee,Xavier Lee,Arnold Liao,Jennifer A. Loch,Mitch Lok,Shujun Luo,Radhika M. Mammen,John W. Martin,Patrick Mccauley,Paul McNitt,Parul Mehta,Keith W. Moon,Joe W. Mullens,Taksina Newington,Zemin Ning,Bee Ling Ng,Sonia M. Novo,Michael J. O'Neill,Mark A. Osborne,Mark A. Osborne,Andrew Osnowski,Omead Ostadan,Lambros L. Paraschos,Lea Pickering,Andrew C. Pike,Alger C. Pike,D. Chris Pinkard,Daniel P. Pliskin,Joe Podhasky,Victor J. Quijano,Come Raczy,Vicki H. Rae,Stephen Rawlings,Ana Chiva Rodriguez,Phyllida M. Roe,John Rogers,Maria Candelaria Rogert Bacigalupo,Nikolai Romanov,Anthony Romieu,Rithy K. Roth,Natalie J. Rourke,Silke Ruediger,Eli Rusman,Raquel Maria Sanches-Kuiper,Martin R. Schenker,Josefina M. Seoane,Richard Shaw,Mitch K. Shiver,Steven W. Short,Ning Sizto,Johannes P. Sluis,Melanie Anne Smith,Jean Ernest Sohna Sohna,Eric J. Spence,Kim B. Stevens,Neil Sutton,Lukasz Szajkowski,Carolyn Tregidgo,Gerardo Turcatti,Stephanie Vandevondele,Yuli Verhovsky,Selene M. Virk,Suzanne Wakelin,Gregory C. Walcott,Jingwen Wang,Graham John Worsley,Juying Yan,Ling Yau,Mike Zuerlein,Jane Rogers,James C. Mullikin,Matthew E. Hurles,Nick J. McCooke,Nick J. McCooke,John Stephen West,Frank L. Oaks,Peter Lundberg,David Klenerman,Richard Durbin,Anthony J. Smith +201 more
TL;DR: An approach that generates several billion bases of accurate nucleotide sequence per experiment at low cost is reported, effective for accurate, rapid and economical whole-genome re-sequencing and many other biomedical applications.
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A comprehensive catalogue of somatic mutations from a human cancer genome
Erin Pleasance,R. Keira Cheetham,Philip J. Stephens,David J. McBride,Sean Humphray,Christopher Greenman,Ignacio Varela,Meng-Lay Lin,Gonzalo R. Ordóñez,Graham R. Bignell,Kai Ye,Julie Alipaz,Markus J. Bauer,David Beare,Adam Butler,Richard J. Carter,Lina Chen,Anthony J. Cox,Sarah Edkins,Paula Kokko-Gonzales,Niall Anthony Gormley,Russell J. Grocock,Christian D. Haudenschild,Matthew M. Hims,Terena James,Mingming Jia,Zoya Kingsbury,Catherine Leroy,John Marshall,Andrew Menzies,Laura Mudie,Zemin Ning,Thomas Royce,Ole Schulz-Trieglaff,Anastassia Spiridou,Lucy Stebbings,Lukasz Szajkowski,Jon W. Teague,David Williamson,Lynda Chin,Mark T. Ross,Peter J. Campbell,David R. Bentley,P. Andrew Futreal,Michael R. Stratton,Michael R. Stratton +45 more
TL;DR: The genomes of a malignant melanoma and a lymphoblastoid cell line from the same person are sequenced, providing the first comprehensive catalogue of somatic mutations from an individual cancer.
NxTrim: optimized trimming of Illumina mate pair reads
Jared O'Connell,Ole Schulz-Trieglaff,Emma Carlson,Matthew M. Hims,Niall Anthony Gormley,Anthony J. Cox +5 more
TL;DR: NxTrim is presented, a tool that strives to discard as little sequence as possible from NMP reads and makes full use of the sequence on both sides of the adapter site to build 'virtual libraries' of mate pairs, paired-end reads and single-ended reads.
176
Retinitis pigmentosa: genes, proteins and prospects.
TL;DR: RP is a heterogeneous group of inherited progressive retinal dystrophies, primarily affecting the peripheral retina, and a number of avenues for possible therapy are being investigated.
109
Mutations in the RP1 gene causing autosomal dominant retinitis pigmentosa
Sara J. Bowne,Stephen P. Daiger,Matthew M. Hims,Melanie M. Sohocki,Kimberly A. Malone,AB McKie,John R. Heckenlively,David G. Birch,Chris F. Inglehearn,Shomi S. Bhattacharya,Alan C. Bird,Lori S. Sullivan +11 more
TL;DR: Based on this study, mutations in RP1 appear to cause at least 7% (17/250) of adRP, and the 5 bp deletion of nucleotides 2280-2284 and the Arg677X nonsense mutation account for 59% of these mutations.
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