Matthew Howell
University of Missouri
17 Papers
21 Citations
Matthew Howell is an academic researcher from University of Missouri. The author has contributed to research in topics: Cell division & FtsZ. The author has an hindex of 8, co-authored 16 publications. Previous affiliations of Matthew Howell include University of Manchester & Westminster College (Missouri).
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Papers
Mini-Tn7 insertion in an artificial attTn7 site enables depletion of the essential master regulator CtrA in the phytopathogen Agrobacterium tumefaciens
TL;DR: This study used a Tn7-based method for inducible control of transcription from an engineered site on the chromosome to deplete the alphaproteobacterial master regulator CtrA and found that depletion of this essential gene results in dramatic rounding of cells, which become nonviable.
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Agrobacterium tumefaciens divisome proteins regulate the transition from polar growth to cell division.
Matthew Howell,Alena Aliashkevich,Kousik Sundararajan,Jeremy J. Daniel,Patrick J. Lariviere,Erin D. Goley,Felipe Cava,Pamela J. B. Brown +7 more
TL;DR: The mechanisms that restrict peptidoglycan biosynthesis to the pole during elongation and re-direct peptidoglucose biosynthesis at the mid-cell during cell division in polar growing Alphaproteobacteria are described in this article.
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Absence of the Polar Organizing Protein PopZ Results in Reduced and Asymmetric Cell Division in Agrobacterium tumefaciens.
Matthew Howell,Alena Aliashkevich,Anne K. Salisbury,Felipe Cava,Grant R. Bowman,Pamela J. B. Brown +5 more
TL;DR: Data suggest that PopZ plays an important role in the regulation of chromosome segregation and cell division in A. tumefaciens, which may allow for the development of innovations to prevent disease or to promote growth during biotechnology applications.
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Building the bacterial cell wall at the pole.
TL;DR: It is illustrated that common themes are emerging in the regulation of polar growth in diverse bacteria, including the use of landmark proteins to direct growth to the pole and coordination of polar Growth with cell-cycle progression.
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Absence of the Min System Does Not Cause Major Cell Division Defects in Agrobacterium tumefaciens.
TL;DR: The data suggest that the Min system contributes to the proper regulation of FtsZ placement and subsequent cell division, and the failure to precisely place FTSZ rings at mid-cell in the min mutants impacts other cell cycle features including chromosome segregation.