Matt Gregas
Boston Children's Hospital
21 Papers
90 Citations
Matt Gregas is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Epilepsy. The author has an hindex of 17, co-authored 21 publications. Previous affiliations of Matt Gregas include Harvard University.
Chat about Author
Papers
Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome
Omar Khwaja,Omar Khwaja,Eugenia Ho,Eugenia Ho,Katherine Barnes,Heather M. O’Leary,Luis M. Pereira,Yaron Finkelstein,Yaron Finkelstein,Charles A. Nelson,Vanessa Vogel-Farley,Geneva DeGregorio,Ingrid A. Holm,Ingrid A. Holm,Umakanth Khatwa,Kush Kapur,Mark E. Alexander,Mark E. Alexander,Deirdre M. Finnegan,Nicole G. Cantwell,Alexandra C. Walco,Leonard Rappaport,Matt Gregas,Raina N. Fichorova,Michael W. Shannon,Michael W. Shannon,Mriganka Sur,Walter E. Kaufmann +27 more
TL;DR: The data indicate that IGF-1 is safe and well tolerated in girls with RTT and, as demonstrated in preclinical studies, ameliorates certain breathing and behavioral abnormalities.
Characterizing spinal muscular atrophy with electrical impedance myography.
Seward B. Rutkove,Jeremy M. Shefner,Matt Gregas,Hailly Butler,Jayson Caracciolo,Connie H. Lin,Patricia M. Fogerson,Phillip Mongiovi,Basil T. Darras +8 more
TL;DR: Electrical impedance myography is a non‐invasive, painless technique for the evaluation of neuromuscular disease, and here it is confirmed that EIM can accurately categorize patients with SMA.
103
Longer duration of epilepsy and earlier age at epilepsy onset correlate with impaired cognitive development in infancy.
Martina Vendrame,Martina Vendrame,Andreas V. Alexopoulos,Katrina Boyer,Matt Gregas,Matt Gregas,Jennifer S. Haut,Tara T. Lineweaver,Elaine Wyllie,Tobias Loddenkemper +9 more
TL;DR: The results suggest that duration of epilepsy and age at onset may be the best developmental predictors during the first years of life in patients with epilepsy.
94
Treatment of unilateral coronal synostosis by endoscopic strip craniectomy or fronto-orbital advancement: Ophthalmologic findings.
TL;DR: Children with unilateral coronal synostosis treated by early endoscopic strip craniectomy may develop less severe V-pattern strabismus, excyclotorsion, and range of aniso-astigmatism than those treated by later fronto-orbital advancement.
64
Electrical impedance myography in spinal muscular atrophy: a longitudinal study.
TL;DR: EIM could detect non–mass‐dependent muscle maturation in healthy children and in contrast, the muscle in children with SMA, as measured by EIM, was virtually static, showing no evidence of growth or active deterioration.
62