Mathilde Svendstrup
University of Copenhagen
14 Papers
19 Citations
Mathilde Svendstrup is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Body mass index & Weight loss. The author has an hindex of 7, co-authored 14 publications. Previous affiliations of Mathilde Svendstrup include Steno Diabetes Center & Bispebjerg Hospital.
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Papers
FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials
Katherine M. Livingstone,Katherine M. Livingstone,Carlos Celis-Morales,Carlos Celis-Morales,George D. Papandonatos,Bahar Erar,Jose C. Florez,Jose C. Florez,Kathleen A. Jablonski,Cristina Razquin,Cristina Razquin,Amelia Marti,Amelia Marti,Yoriko Heianza,Tao Huang,Tao Huang,Frank M. Sacks,Mathilde Svendstrup,Xuemei Sui,Timothy S. Church,Tiina Jääskeläinen,Tiina Jääskeläinen,Jaana Lindström,Jaakko Tuomilehto,Matti Uusitupa,Tuomo Rankinen,Wim H. M. Saris,Torben Hansen,Oluf Pedersen,Arne Astrup,Thorkild I. A. Sørensen,Lu Qi,Lu Qi,George A. Bray,Miguel Ángel Martínez-González,Miguel Ángel Martínez-González,J. Alfredo Martínez,J. Alfredo Martínez,Paul W. Franks,Paul W. Franks,Jeanne M. McCaffery,Jose Lara,Jose Lara,John C. Mathers +43 more
TL;DR: Findings show that individuals carrying the minor allele respond equally well to dietary, physical activity, or drug based weight loss interventions and thus genetic predisposition to obesity associated with the FTO minor allele can be at least partly counteracted through such interventions.
Patients With Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated With Reactive Hypoglycemia.
Louise Hyltén-Cavallius,Eva W. Iepsen,Nicolai J. Wewer Albrechtsen,Mathilde Svendstrup,Anniek F. Lubberding,Bolette Hartmann,Thomas Jespersen,Allan Linneberg,Michael Christiansen,Henrik Vestergaard,Oluf Pedersen,Jens J. Holst,Jørgen K. Kanters,Torben Hansen,Signe S. Torekov +14 more
TL;DR: Besides a prolonged cardiac repolarization phase, LQT2 patients display increased GLP-1, GIP, and insulin secretion and defective glucagon secretion, causing decreased plasma glucose and thus increased risk of hypoglycemia.
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Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations.
Cæcilie Trier,Cæcilie Trier,Mette Hollensted,Theresia M. Schnurr,Morten Asp Vonsild Lund,Morten Asp Vonsild Lund,Tenna Ruest Haarmark Nielsen,Gao Rui,Ehm A. Andersson,Mathilde Svendstrup,Dorthe S. Bille,Dorthe S. Bille,Anette P. Gjesing,Cilius Esmann Fonvig,Cilius Esmann Fonvig,Christine Frithioff-Bøjsøe,Christine Frithioff-Bøjsøe,Marie Balslev-Harder,Shi Quan,Michael Gamborg,Oluf Pedersen,Lars Ängquist,Jens-Christian Holm,Jens-Christian Holm,Torben Hansen +24 more
TL;DR: In contrast to noncarriers, carriers of damaging or unresolved MC4R mutations failed to reduce their BMI SDS during obesity treatment, indicating a need for personalized treatment based on theMC4R genotype.
Genetic Determinants of Weight Loss After Bariatric Surgery
Martin Aasbrenn,Martin Aasbrenn,Theresia M. Schnurr,Christian Theil Have,Mathilde Svendstrup,Dorte Lindqvist Hansen,Dorte Worm,Marie Balslev-Harder,Mette Hollensted,Niels Grarup,Kristoffer Sølvsten Burgdorf,Henrik Vestergaard,Henrik Vestergaard,Oluf Pedersen,Thorkild I. A. Sørensen,Mogens Fenger,Sten Madsbad,Torben Hansen +17 more
TL;DR: A genetic risk score was associated with EBMIL after bariatric surgery, but may not yet be applicable to clinical practice as a result of searches among known adiposity-related single nucleotide polymorphisms (SNPs).
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A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents.
Tenna Ruest Haarmark Nielsen,Emil V. R. Appel,Mathilde Svendstrup,Johanne Dam Ohrt,Maria Dahl,Cilius Esmann Fonvig,Cilius Esmann Fonvig,Mette Hollensted,Christian Theil Have,Haja N. Kadarmideen,Oluf Pedersen,Torben Hansen,Jens-Christian Holm,Jens-Christian Holm,Niels Grarup +14 more
TL;DR: In a group of Danish children and adolescents, four loci previously associated with plasma TSH concentrations in adults, were associated with outpatient thyroid hormone levels in children, suggesting comparable genetic determinants of thyroid function in adults and children.