Mathias De Roo
University of Geneva
21 Papers
6 Citations
Mathias De Roo is an academic researcher from University of Geneva. The author has contributed to research in topics: Dendritic spine & Dendritic filopodia. The author has an hindex of 17, co-authored 21 publications. Previous affiliations of Mathias De Roo include Geneva College.
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Papers
Cocaine disinhibits dopamine neurons by potentiation of GABA transmission in the ventral tegmental area
Christina Bocklisch,Vincent Pascoli,Jovi C. Y. Wong,David R. C. House,Cédric Yvon,Mathias De Roo,Kelly R. Tan,Christian Lüscher,Christian Lüscher +8 more
TL;DR: Cocaine-evoked potentiation of GABA release from D1R-MSNs affected drug-adaptive behavior, which identifies these neurons as a promising target for novel addiction treatments.
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Dendritic spine formation and stabilization
TL;DR: Together these new data provide a better understanding of the mechanisms, speed and steps leading to the establishment of a stable excitatory synapse and suggest that activity and induction of plasticity participate to the selection of persistent spines.
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Volatile anesthetics rapidly increase dendritic spine density in the rat medial prefrontal cortex during synaptogenesis.
TL;DR: In this article, exposure time-dependent effects of volatile anesthetics on neuronal cytoarchitecture in 16-day-old rats, a developmental stage characterized by intense synaptogenesis in the cerebral cortex, were evaluated.
LTP promotes a selective long-term stabilization and clustering of dendritic spines.
TL;DR: Using repetitive confocal imaging on hippocampal organotypic cultures, it is found that learning-related patterns of activity that induce long-term potentiation act as a selection mechanism for the stabilization and localization of spines.
Developmental Stage-dependent persistent impact of propofol anesthesia on dendritic spines in the rat medial prefrontal cortex.
Adrian Briner,Irina Nikonenko,Mathias De Roo,Alexandre Dayer,Dominique Muller,Laszlo Vutskits +5 more
TL;DR: The new results demonstrate that propofol anesthesia can rapidly induce significant changes in dendritic spine density and that these effects are developmental stage-dependent, persist into adulthood, and are accompanied by alterations in synapse number.