Masanori Nakata
Jichi Medical University
66 Papers
261 Citations
Masanori Nakata is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Insulin & Hypothalamus. The author has an hindex of 28, co-authored 62 publications. Previous affiliations of Masanori Nakata include Wakayama Medical University.
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Papers
Regulation of voltage-gated K+ channels by glucose metabolism in pancreatic β-cells
Masashi Yoshida,Katsuya Dezaki,Shiho Yamato,Atsushi Aoki,Hitoshi Sugawara,Hideo Toyoshima,San-e Ishikawa,Masanobu Kawakami,Masanori Nakata,Toshihiko Yada,Masafumi Kakei +10 more
TL;DR: It is concluded that glucose metabolism regulates Kv2.1 channels in rats β‐cells via altering MgATP levels through down‐regulation of delayed rectifier‐type K+ channels.
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Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation
TL;DR: Results demonstrate that insulin PDK1-dependently preferentially activates PVN magnocellular oxytocin neurons to release Oxytocin into circulation, possibly serving as a mechanism for the interaction between metabolism and perinatal functions.
Role of NUCB2/nesfatin-1 in glucose control: diverse functions in islets, adipocytes and brain.
Masanori Nakata,Toshihiko Yada +1 more
TL;DR: The physiological and pathophysiological roles of the nesfatin-1/NUCB2 in glucose and energy metabolism are discussed and its regulatory processes may provide novel targets for treating associated diseases of the metabolic syndrome.
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Islet β-cell-produced NUCB2/nesfatin-1 maintains insulin secretion and glycemia along with suppressing UCP-2 in β-cells.
Yifei Yang,Boyang Zhang,Boyang Zhang,Masanori Nakata,Masanori Nakata,Jun Nakae,Masatomo Mori,Toshihiko Yada,Toshihiko Yada +8 more
TL;DR: Results show impaired GSIS possibly associated with UCP-2 overexpression in NUCB2-silenced β-cells, suggesting that β-cell-produced N UCB2/nesfatin-1 maintains GSIS and thereby glycemia.
PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis
TL;DR: A novel role of PDK1-Foxo1 pathway of AgRP neurons in controlling bone metabolism primarily via GHRH-GH-IGF-1 axis is revealed.
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