Masakazu Sato
Taisho Pharmaceutical Co.
128 Papers
666 Citations
Masakazu Sato is an academic researcher from Taisho Pharmaceutical Co.. The author has contributed to research in topics: Alkyl & Alkoxy group. The author has an hindex of 18, co-authored 128 publications. Previous affiliations of Masakazu Sato include IBM.
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Papers
Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke.
Noriyuki Miyata,Takayuki Seki,Yu Tanaka,Tomohiro Omura,Kazuo Taniguchi,Mariko Doi,Kagumi Bandou,Shunichi Kametani,Masakazu Sato,Shigeru Okuyama,Liana Cambj-Sapunar,David R. Harder,Richard J. Roman +12 more
TL;DR: Blockade of the synthesis of 20-HETE with TS-011 opposes cerebral vasospasm following SAH and reduces infarct size in ischemic models of stroke.
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Pyrazole and isoxazole derivatives as new, potent, and selective 20-hydroxy-5,8,11,14-eicosatetraenoic acid synthase inhibitors.
Toshio Nakamura,Masakazu Sato,Hiroyuki Kakinuma,Noriyuki Miyata,Kazuo Taniguchi,Kagumi Bando,and Ayumi Koda,Kazuya Kameo +7 more
TL;DR: In a previous study, the preparation of an injectable formulation of HET0016 was limited by its poor solubility under neutral conditions and instability under acidic conditions, but other azole derivatives showed potent and selective activities with improved stability.
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Imidazole derivatives as new potent and selective 20-HETE synthase inhibitors
Toshio Nakamura,Hiroyuki Kakinuma,Hiroki Umemiya,Hideaki Amada,Noriyuki Miyata,Kazuo Taniguchi,Kagumi Bando,Masakazu Sato +7 more
TL;DR: Some derivatives of imidazole 1 which had an amino group on the side chain showed potent and selective inhibitory activity, and found that a dimethylaminohexyloxy derivative showed potency and selectivity for cytochrome P450s.
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Patent
2-Azetidinone derivatives
Yutaka Kawashima,Masakazu Sato,Masahiro Kawase,Yoshiaki Watanabe,Katsuo Hatayama +4 more
- 20 Oct 1989
TL;DR: In this article, Azetizinone derivatives, useful as blood platelet aggregation inhibiting agents, are those of the formula: Somewhat (in which R 1 is a halogen atom a C 1 -C 4 alkyl group, a c 1-C 4 alkoxy group or an alkoxy carbonyl group in which the alkoxy groups is a C 2 -C4 alkyyl group or a pyridyl group; n is an integer of from 2 to 10; and salts thereof).
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