Masakatsu Watanabe
University of Maryland, Baltimore
7 Papers
1 Citations
Masakatsu Watanabe is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 4 publications.
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Papers
All-atom empirical potential for molecular modeling and dynamics studies of proteins.
Alexander D. MacKerell,D. Bashford,M. Bellott,Roland L. Dunbrack,Jeffrey D. Evanseck,Martin J. Field,Stefan Fischer,Jiali Gao,H. Guo,S. Ha,Diane Joseph-McCarthy,L. Kuchnir,K. Kuczera,F. T. K. Lau,C. Mattos,Stephen W. Michnick,Thien H. Ngo,D. T. Nguyen,B. Prodhom,W. E. Reiher,Benoît Roux,M. Schlenkrich,Jeremy C. Smith,Roland H. Stote,John E. Straub,Masakatsu Watanabe,J. Wiórkiewicz-Kuczera,D. Yin,Martin Karplus +28 more
TL;DR: The results demonstrate that use of ab initio structural and energetic data by themselves are not sufficient to obtain an adequate backbone representation for peptides and proteins in solution and in crystals.
•Book
Computational Biochemistry And Biophysics
Oren M. Becker,Alex D. MacKerell,Benoît Roux,Masakatsu Watanabe +3 more
- 01 Jan 2016
TL;DR: This work describes the development and application of the RISM-SCF/MCSCF approach for the chemical processes in solutions nucleic acids simulations membrane simulations, and the design and design of computer-aided drug design.
521
Somatic GJA4 gain-of-function mutation in orbital cavernous venous malformations
Hiroki Hongo,Satoru Miyawaki,Yumiko Teranishi,Jun Mitsui,Hiroto Katoh,Daisuke Komura,Kinya Tsubota,Takashi Matsukawa,Masakatsu Watanabe,Masakazu Kurita,Jun Yoshimura,Shogo Dofuku,Kenta Ohara,Daiichiro Ishigami,Atsushi Okano,Motoi Kato,Fumihiko Hakuno,Ayaka Takahashi,Akiko Kunita,Hiroyuki Ishiura,Masahiro Shin,Hirofumi Nakatomi,Toshitaka Nagao,Hiroshi Goto,Shinichiro Takahashi,Tetsuo Ushiku,Shumpei Ishikawa,Mutsumi Okazaki,Shinichi Morishita,Shoji Tsuji,Nobuhito Saito +30 more
TL;DR: In this paper , the authors identify a somatic missense mutation, c.121G > T (p.Gly41Cys) in GJA4, which encodes a transmembrane protein that is a component of gap junctions and hemichannels in the vascular system.
All-Atom Simulations Uncover Structural and Dynamical Properties of STING Proteins in the Membrane System
TL;DR: This research investigated ligand-bound closed (apo) and lig and-unbound open (holo) forms of STING in the membrane system by comparing their conformational and dynamical differences, and provides clues for understanding the mechanism of the STING signaling pathway.
Fish-specific N-terminal domain sequence in Connexin 39.4 plays an important role in zebrafish stripe formation by regulating the opening and closing of gap junctions and hemichannels.
TL;DR: In this article , the role of serine/arginine (SR) residues in channel properties of Cx39.4 was investigated, and the effect of each mutation on fish skin patterning was evaluated.