Masahiko Higashiyama
Osaka University
243 Papers
1.9K Citations
Masahiko Higashiyama is an academic researcher from Osaka University. The author has contributed to research in topics: Lung cancer & Survival rate. The author has an hindex of 50, co-authored 241 publications.
Chat about Author
Papers
Cystic mucinous adenocarcinoma of the lung. Two cases of cystic variant of mucus-producing lung adenocarcinoma.
TL;DR: The present tumors are considered to be a cystic variant of mucus-producing lung adenocarcinoma that expands grossly by storing mucus.
Adjuvant gefitinib versus cisplatin/vinorelbine in Japanese patients with completely resected, EGFR-mutated, stage II-III non-small cell lung cancer (IMPACT, WJOG6410L): A randomized phase 3 trial.
Hirohito Tada,Tetsuya Mitsudomi,Takeharu Yamanaka,Kenji Sugio,Masahiro Tsuboi,Isamu Okamoto,Yasuo Iwamoto,Noriaki Sakakura,Shunichi Sugawara,Shinji Atagi,Toshiaki Takahashi,Hidetoshi Hayashi,Morihito Okada,Hiroshige Yoshioka,Hidetoshi Inokawa,Kazuhisa Takahashi,Masahiko Higashiyama,Ichiro Yoshino,Kazuhiko Nakagawa +18 more
TL;DR: Adjuvant gefitinib appeared to prevent early relapse, but did not significantly prolong DFS or OS in patients with completely resected stage II–III, EGFR-mutated NSCLC.
Oncologic Outcomes of Segmentectomy Versus Lobectomy for Clinical T1a N0 M0 Non-Small Cell Lung Cancer
Ken Kodama,Masahiko Higashiyama,Jiro Okami,Toshiteru Tokunaga,Fumio Imamura,Tomio Nakayama,Atsuo Inoue,Keiko Kuriyama +7 more
TL;DR: The results suggest that the oncologic outcome of segmentectomy vs lobectomy is similar in this cohort of c-T1a N0 M0 NSCLC patients, and these results will be validated by large-scale, prospective, randomized trials.
Dramatic response of postthymomectomy myasthenia gravis with multiple lung nodules to corticosteroids.
TL;DR: Steroid therapy induced remarkable regression of the lung nodules that has persisted for more than 11 months and markedly decreased the clinical severity of her myasthenia gravis markedly decreased and recovered to the extent of permitting her to return to normal life.
Mutations in exon 7 and 8 of p53 as poor prognostic factors in patients with non-small cell lung cancer.
Cheng-long Huang,Toshihiko Taki,Masashi Adachi,T Konishi,Masahiko Higashiyama,Masayuki Miyake +5 more
TL;DR: Investigation of mutations in exon 8, especially codon 273 mutation and mutant H2 α helix was considered to be a clinically useful approach for determining the prognosis of patients with NSCLC, suggesting that abnormal conformation of H2α helix might play an important role not only in the loss of normal function but also in the acquisition of tumorigenesis.