Maryam Faiz
University of Toronto
25 Papers
69 Citations
Maryam Faiz is an academic researcher from University of Toronto. The author has contributed to research in topics: Glial fibrillary acidic protein & Progenitor cell. The author has an hindex of 14, co-authored 19 publications. Previous affiliations of Maryam Faiz include University of Gothenburg & Autonomous University of Barcelona.
Chat about Author
Papers
Astrocytes negatively regulate neurogenesis through the Jagged1-mediated Notch pathway.
Ulrika Wilhelmsson,Maryam Faiz,Yolanda de Pablo,Marika Sjöqvist,Marika Sjöqvist,Daniel Andersson,Åsa Widestrand,Maja Potokar,Matjaž Stenovec,Peter L. P. Smith,Noriko Shinjyo,Tulen Pekny,Robert Zorec,Robert Zorec,Anders Ståhlberg,Marcela Pekna,Cecilia Sahlgren,Cecilia Sahlgren,Milos Pekny +18 more
TL;DR: Astrocytes negatively regulate neurogenesis through the Notch pathway, and endocytosis of Notch ligand Jagged1 in astroCytes and Notch signaling from astrocyte to neural stem/progenitor cells depends on the intermediate filament proteins GFAP and vimentin.
148
Cu/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury
TL;DR: It is shown that, in the intact immature brain, the expression of Cu/Zn SOD was mainly found in neurons, and when damage occurs, a strong and very rapid downregulation of this enzyme precedes neuronal degeneration, and is followed by an upregulation of Cu/(Zn) SOD in astroglial cells.
Survivin and heat shock protein 25/27 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain
TL;DR: Investigation of the astrocytic colocalization of cleaved caspase-3 and several anti-apoptotic proteins of the inhibitor of apoptosis proteins family (IAPs) concluded that primarily survivin and Hsp25/27 may participate in the inhibition of casp enzyme-3 in reactive astroCytes and may be involved in protecting astroicytes after injury.
38
Substantial migration of SVZ cells to the cortex results in the generation of new neurons in the excitotoxically damaged immature rat brain.
TL;DR: It is demonstrated that NMDA-induced injury forces endogenous Cell Tracker Green (CTG) labeled VZ/SVZ precursors out of the SVZ into the neurodegenerating cortex.
36
Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease
Tulen Pekny,Maryam Faiz,Ulrika Wilhelmsson,Maurice A. Curtis,Radoslav Matej,Omar Skalli,Milos Pekny +6 more
TL;DR: It is shown that synemin is expressed in reactive astrocytes inAxD, and is also present in Rosenthal fibers, and the potential role of synemin in AxD pathogenesis remains to be investigated.
35