Martin O. Leach
The Royal Marsden NHS Foundation Trust
514 Papers
6.4K Citations
Martin O. Leach is an academic researcher from The Royal Marsden NHS Foundation Trust. The author has contributed to research in topics: Magnetic resonance imaging & Medicine. The author has an hindex of 78, co-authored 512 publications. Previous affiliations of Martin O. Leach include Engineering and Physical Sciences Research Council & University of Minnesota.
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Papers
Nonrigid registration using free-form deformations: application to breast MR images
TL;DR: The results clearly indicate that the proposed nonrigid registration algorithm is much better able to recover the motion and deformation of the breast than rigid or affine registration algorithms.
American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography
Debbie Saslow,Carla Boetes,Wylie Burke,Steven E. Harms,Martin O. Leach,Constance D. Lehman,Elizabeth A. Morris,Etta D. Pisano,Mitchell D. Schnall,Stephen F. Sener,Robert A. Smith,Ellen Warner,Martin J. Yaffe,Kimberly S. Andrews,Christy A. Russell +14 more
TL;DR: There are several risk subgroups for which the available data are insufficient to recommend for or against screening, including women with a personal history of breast cancer, carcinoma in situ, atypical hyperplasia, and extremely dense breasts on mammography.
2.7K
Imaging biomarker roadmap for cancer studies.
James P B O'Connor,Eric O. Aboagye,Judith E. Adams,Hugo J.W.L. Aerts,Hugo J.W.L. Aerts,Sally F. Barrington,Ambros J. Beer,Ronald Boellaard,Sarah E. Bohndiek,J. Michael Brady,Gina Brown,David L. Buckley,Thomas L. Chenevert,Laurence P. Clarke,Sandra Collette,Gary Cook,Nandita M. deSouza,John Dickson,Caroline Dive,Jeffrey L. Evelhoch,Corinne Faivre-Finn,Ferdia A. Gallagher,Fiona J. Gilbert,Robert J. Gillies,Vicky Goh,John R. Griffiths,Ashley M. Groves,Steve Halligan,Adrian L. Harris,David J. Hawkes,Otto S. Hoekstra,Erich P. Huang,Brian Hutton,Edward F. Jackson,Gordon C Jayson,Andrew J. I. Jones,Dow-Mu Koh,Denis Lacombe,Philippe Lambin,Nathalie Lassau,Martin O. Leach,Ting-Yim Lee,Edward Leen,Jason S. Lewis,Yan Liu,Mark F. Lythgoe,Prakash Manoharan,Ross J. Maxwell,Kenneth A. Miles,Bruno Morgan,Steve Morris,Tony Ng,Anwar R. Padhani,Geoff J M Parker,Mike Partridge,Arvind P. Pathak,Arvind P. Pathak,Andrew C. Peet,Shonit Punwani,Andrew R. Reynolds,Simon P. Robinson,Lalitha K. Shankar,Ricky A. Sharma,Dmitry Soloviev,Sigrid Stroobants,Daniel C. Sullivan,Stuart A. Taylor,Paul S. Tofts,Gillian M. Tozer,Marcel van Herk,Simon Walker-Samuel,James Wason,Kaye J. Williams,Paul Workman,Thomas E. Yankeelov,Kevin M. Brindle,Lisa M. McShane,Alan Jackson,John C. Waterton +78 more
TL;DR: Experts assembled to review, debate and summarize the challenges of IB validation and qualification produced 14 key recommendations for accelerating the clinical translation of IBs, which highlight the role of parallel (rather than sequential) tracks of technical validation, biological/clinical validation and assessment of cost-effectiveness.
Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research
John Kurhanewicz,Daniel B. Vigneron,Kevin M. Brindle,Eduard Y. Chekmenev,Arnaud Comment,Charles H. Cunningham,Ralph J. DeBerardinis,Gary G. R. Green,Martin O. Leach,Sunder S. Rajan,Rahim R. Rizi,Brian D. Ross,Warren S. Warren,Craig R. Malloy +13 more
TL;DR: The known abnormalities in cancer metabolism, the value and limitations of current imaging methods for metabolism, and the principles of hyperpolarization are summarized.
Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer; a prospective multicentre cohort study (MARIBS)
Martin O. Leach,Caroline Boggis,Adrian K. Dixon,Douglas F. Easton,RA Eles,D G R Evans,Fiona J. Gilbert,I Griebsch,Rebecca Hoff,Preminda Kessar,Lakhani,Sue Moss,Ashutosh Nerurkar,Anwar R. Padhani,Linda Pointon,Deborah J. Thompson,Ruth Warren +16 more
- 01 Jan 2005
TL;DR: The findings indicate that CE MRI is more sensitive than mammography for cancer detection, and annual screening, combining CE MRI and mammography, would detect most tumours in this risk group.
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