Martin G. Pomper
Johns Hopkins University School of Medicine
682 Papers
3.1K Citations
Martin G. Pomper is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Medicine & Prostate cancer. The author has an hindex of 80, co-authored 601 publications. Previous affiliations of Martin G. Pomper include University of Illinois at Chicago & Johns Hopkins University.
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Papers
Evaluation of a PSMA-targeted BNF nanoparticle construct
Babak Behnam Azad,Sangeeta Ray Banerjee,Mrudula Pullambhatla,Silvia H. De Paoli Lacerda,Catherine A. Foss,Yuchuan Wang,Robert Ivkov,Martin G. Pomper +7 more
TL;DR: The synthesis of a PSMA-targeted bionized nanoferrite (BNF) nanoparticle and its biological evaluation in an experimental model of PCa reveal properties conducive to targeted imaging such as stealth, prolonged circulation time and enhanced clearance from non-target sites.
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Radiolabeled anti-claudin 4 and anti-prostate stem cell antigen: initial imaging in experimental models of pancreatic cancer.
Catherine A. Foss,James Fox,Georg Feldmann,Anirban Maitra,Christine Iacobuzio-Donohue,Scott E. Kern,Ralph H. Hruban,Martin G. Pomper +7 more
TL;DR: Both anti-claudin 4 and anti-PSCA demonstrate promise as radiodiagnostic and possibly radiotherapeutic agents for human pancreatic cancers.
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Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma
Jong-Sung Park,Yumin Oh,Yong Joo Park,Ogyi Park,Hoseong S. Yang,Stephanie Slania,Laura K. Hummers,Ami A. Shah,Hyoung Tae An,Jiyeon Jang,Maureen R. Horton,Joseph Y. Shin,Harry C. Dietz,Eric Song,Dong Hee Na,Eun Ji Park,Kwangmeyung Kim,Kang Choon Lee,Viktor V. Roschke,Justin Hanes,Martin G. Pomper,Martin G. Pomper,Seulki Lee,Seulki Lee +23 more
TL;DR: The authors show that a bioengineered recombinant human TRAIL ligand reverses established fibrosis in mouse models of scleroderma by targeting the death receptor 5 and inducing apoptosis of myofibroblasts.
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Narrative review of generative adversarial networks in medical and molecular imaging
Kazuhiro Koshino,Rudolf A. Werner,Martin G. Pomper,Ralph A. Bundschuh,Fujio Toriumi,Takahiro Higuchi,Steven P. Rowe +6 more
TL;DR: A comprehensive overview for GANs is provided and their usefulness in medical and molecular imaging is discussed on the following topics: data augmentation to increase training data for AI-based computer-aided diagnosis as a solution for the data-hungry nature of such training sets.
(S)-3-(Carboxyformamido)-2-(3-(carboxymethyl)ureido)propanoic Acid as a Novel PSMA Targeting Scaffold for Prostate Cancer Imaging.
Xiaojiang Duan,Futao Liu,Hongmok Kwon,Youngjoo Byun,Il Minn,Xuekang Cai,Jingming Zhang,Martin G. Pomper,Yang Zhi,Xi Zhen,Xing Yang +10 more
TL;DR: (S)-3-(Carboxyformamido)-2-(3-(carboxymethyl)ureido) propanoic acids proved potent PSMA ligands with Ki values ranging from 0.08 nM - 8.98 nM, which are in the range of or are higher in potency compared to previously published Glu-Urea-based ligands.
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