Martin E. Adelson
Rutgers University
92 Papers
553 Citations
Martin E. Adelson is an academic researcher from Rutgers University. The author has contributed to research in topics: Bacterial vaginosis & Gardnerella vaginalis. The author has an hindex of 27, co-authored 89 publications. Previous affiliations of Martin E. Adelson include University of Medicine and Dentistry of New Jersey.
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Papers
Survey of Vaginal-Flora Candida Species Isolates from Women of Different Age Groups by Use of Species-Specific PCR Detection
John-Paul Vermitsky,Matthew J. Self,Sean G. Chadwick,Jason P. Trama,Martin E. Adelson,Eli Mordechai,Scott E. Gygax +6 more
TL;DR: A retrospective survey of 93,775 samples testing positive in Candida species-specific PCR tests performed on cervicovaginal swabs over a 4-year period demonstrated consistent yearly distributions of Candida albicans, but the species distributions among different age groups revealed increases in the percentages of non-albicans species with increases in age.
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Trichomonas vaginalis Metronidazole Resistance Is Associated with Single Nucleotide Polymorphisms in the Nitroreductase Genes ntr4Tv and ntr6Tv
Teresa E. Paulish-Miller,Peter Augostini,Jessica A. Schuyler,William L. Smith,Eli Mordechai,Martin E. Adelson,Scott E. Gygax,William Evan Secor,David W. Hilbert +8 more
TL;DR: These SNPs were associated with one of two distinct T. vaginalis populations identified by multilocus sequence typing, yet one SNP (ntr6Tv A238T), which results in a premature stop codon, was associated with resistance independent of population structure and may be of diagnostic value.
Atopobium vaginae triggers an innate immune response in an in vitro model of bacterial vaginosis
TL;DR: The results suggest that Atopobium vaginae stimulates an innate immune response from vaginal epithelial cells, leading to localized cytokine and defensin production, and possibly contributes to the pathogenesis of bacterial vaginosis.
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Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors
Michael Oertel,Richard Rosencrantz,Richard Rosencrantz,Yuan-Qing Chen,Prashanthi N. Thota,Jaswinderpal S. Sandhu,Mariana D. Dabeva,Annmarie L. Pacchia,Martin E. Adelson,Joseph P. Dougherty,David A. Shafritz +10 more
TL;DR: Fetal hepatoblasts (liver stem/progenitor cells) can serve as efficient vehicles for ex vivo gene therapy and suggest that liver‐based genetic disorders that do not shorten hepatocyte longevity or cause liver damage, such as phenylketonuria, hyperbilirubinemias, familial hypercholesterolemia, primary oxalosis, and factor IX deficiency, might be amenable to treatment by this approach.
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Development and Validation of a Highly Accurate Quantitative Real-Time PCR Assay for Diagnosis of Bacterial Vaginosis
David W. Hilbert,William L. Smith,Sean G. Chadwick,Geoffrey Toner,Eli Mordechai,Martin E. Adelson,Tina Aguin,Jack D. Sobel,Scott E. Gygax +8 more
TL;DR: In this paper, the authors used a logistic regression model to identify the organisms for which quantification provided the most accurate diagnosis of symptomatic BV, as defined by Amsel's criteria and Nugent scoring, with 92% sensitivity, 95% specificity, 94% positive predictive value, and 94% negative predictive value.
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