Markus Falk
3 Papers
50 Citations
Markus Falk is an academic researcher. The author has contributed to research in topics: Apoptosis & FADD. The author has an hindex of 2, co-authored 3 publications.
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Papers
Caspase Inhibition Blocks Human T Cell Proliferation by Suppressing Appropriate Regulation of IL-2, CD25, and Cell Cycle-Associated Proteins
TL;DR: It is shown that proliferation of human T cells in response to a specific antigenic stimulus is completely prevented by caspase inhibition, and this lack of proliferation is due to a failure to initiate cell cycle progression, but not the result of increased T cell death.
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Caspases and proliferation
TL;DR: Facts and hypotheses about potential junctions, coupling the opposing signals leading to death or proliferation are summarized and under which circumstances active caspases might confer to either pathway are discussed.
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The Fas-associated death domain protein/caspase-8/c-FLIP signaling pathway is involved in TNF-induced activation of ERK
TL;DR: Analysis of TNF-induced ERK activation in various human and murine cell lines shows that it occurs in a cell-type-specific manner, and provides evidence for the involvement of the signaling components Fas-associated death domain protein (FADD), caspase-8, and c-FLIP in the pathway activating ERK in response to TNF.