Markus Eyholzer
University of Ottawa
9 Papers
188 Citations
Markus Eyholzer is an academic researcher from University of Ottawa. The author has contributed to research in topics: Microreactor & Micro heat exchanger. The author has an hindex of 8, co-authored 9 publications.
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Papers
Microreactors / Industry Perspective Industrial design, scale-up, and use of microreactors
Dominique Roberge,Michael Gottsponer,Markus Eyholzer,Norbert Kockmann +3 more
- 01 Jan 2009
TL;DR: In this paper, the authors focus on the design and scale up strategy of microreactors and develop a reactor technology that can cope with tiny flow (few mL/min) required during pre-clinical studies up to larger flow rates (several hundreds of mL/m) necessary for phase III clinical trials.
77
Development of an Industrial Multi‐Injection Microreactor for Fast and Exothermic Reactions – Part II
Dominique M. Roberge,Nikolaus Bieler,Meinrad Mathier,Markus Eyholzer,Bertin Zimmermann,Philippe J. Barthe,Celine Guermeur,Olivier Lobet,Maxime Moreno,Pierre Woehl +9 more
TL;DR: In this article, a Grignard reaction performed in a micro-reactor is presented, which is of type A (highly exothermic and very rapid) and has a low yield which is attributed to a hot spot formed in the mixing zone of the reactor.
72
•Journal Article
Industrial design, scale-up, and use of microreactors
TL;DR: In this paper, the authors focus on the design and scale up strategy of microreactors and develop a reactor technology that can cope with tiny flow (few mL/min) required during pre-clinical studies up to larger flow rates (several hundreds of mL/m) necessary for phase III clinical trials.
65
Local and overall heat transfer of exothermic reactions in microreactor systems
Eric Mielke,Patrick Plouffe,Nikhil Koushik,Markus Eyholzer,Michael Gottsponer,Norbert Kockmann,Arturo Macchi,Dominique M. Roberge +7 more
TL;DR: In this article, non-reactive and reactive heat transfer experiments were performed in the FlowPlate® system manufactured by Ehrfeld Mikrotechnik, which is composed of alternating reactor and heat transfer fluid plates within a rack.
33
Control of Hazardous Processes in Flow: Synthesis of 2-Nitroethanol
Dominique M. Roberge,Christian Noti,Eberhard Irle,Markus Eyholzer,Bruno Rittiner,Penn Gerhard,Gottfried Sedelmeier,Berthold Schenkel +7 more
TL;DR: In this article, the authors describe a methodology for developing flow processes based on a proof of concept, an optimization and modeling analysis, and a long run study in a mini-plant.