Mark W. Cunningham
University of Mississippi Medical Center
77 Papers
348 Citations
Mark W. Cunningham is an academic researcher from University of Mississippi Medical Center. The author has contributed to research in topics: Preeclampsia & Medicine. The author has an hindex of 20, co-authored 70 publications. Previous affiliations of Mark W. Cunningham include Florida Fish and Wildlife Conservation Commission & Johns Hopkins University.
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Papers
The role of inflammation in the pathology of preeclampsia.
Ashlyn C Harmon,Denise C. Cornelius,Lorena M. Amaral,Jessica L. Faulkner,Mark W. Cunningham,Kedra Wallace,Babbette LaMarca +6 more
TL;DR: These studies show that restoring the balance of the immune system through increasing Tregs, either by adoptive transfer or by infusing IL-10, reduces the blood pressure and pathophysiology associated with placental ischaemia in pregnant rats.
494
Preeclampsia: long-term consequences for vascular health
TL;DR: There is no “cure” for PE except for early delivery of the baby and placenta, leaving PE a health care risk for babies born from PE moms and a risk factor for long-term health in women.
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Role of Mitochondrial Dysfunction and Reactive Oxygen Species in Mediating Hypertension in the Reduced Uterine Perfusion Pressure Rat Model of Preeclampsia.
Venkata Ramana Vaka,Kristen M. McMaster,Mark W. Cunningham,Tarek Ibrahim,Rebekah Hazlewood,Nathan Usry,Denise C. Cornelius,Lorena M. Amaral,Babbette LaMarca +8 more
TL;DR: The purpose of this study was to not only examine the effect of placental ischemia on mitochondrial-mediated oxidative stress in reduced uterine perfusion pressure (RUPP) rat model of preeclampsia but to also examine the role of mitochondrial ROS in contributing to hypertension in response to placentalIschemia.
139
Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches.
Shashank Shekhar,Mark W. Cunningham,Mallikarjuna R. Pabbidi,Shaoxun Wang,George W. Booz,Fan Fan +5 more
TL;DR: Although likely detrimental to the progression of ischemic stroke by inducing inflammation, oxidative stress, and neuronal cell death, 20‐HETE may also reduce susceptibility of onset of ischemic stroke by maintaining autoregulation of cerebral blood flow.
111
Identifying immune mechanisms mediating the hypertension during preeclampsia
Babbette LaMarca,Denise C. Cornelius,Ashlyn C Harmon,Lorena M. Amaral,Mark W. Cunningham,Jessica L. Faulkner,Kedra Wallace +6 more
TL;DR: The purpose of this review is to highlight hypertensive mechanisms stimulated by inflammatory factors in response to placental ischemia, thereby elucidating a role.
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